Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 12.4, Problem 1TYK
A chromatin-remodeling complex may
- change the locations of nucleosomes.
- exchange standard histones for histone variants.
- evict histones.
- do all of the above.
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Which of the following statements concerning eukaryotic chromatin is true.
Histones have an overall negative charge.
Euchromatin is more condensed then heterochromatin.
After replication nucleosomes are made up of a mixture of old and new histone proteins.
Euchromatin is associated with the centromere and telomere regions.
Heterochromatin are regions of active transcription.
The diagram below shows the structure of DNA from the level of a gene to a condensed mitotic chromosome. At each of the four locations marked, indicate how a gene may be regulated by selecting from the choices given. Some answer choices may fit into more than one position; however, you should use each answer choice only once.
Choices given:
Alternative splicing within the gene sequence can lead to different forms of mRNA.
A promoter region can be blocked by another protein.
Histone deacetylation can prevent DNA from unwinding.
A regulatory region can be bound and increase transcription rates.
Describe the mechanism by which histone modifications are established after DNA replication and cell division. What are some things that could go wrong if modifications can't be maintained? Think about what histone modifications do to DNA and why cells maintain parts of their chromosome as heterochromatin.
Chapter 12 Solutions
Principles of Biology
Ch. 12.1 - How does gene regulation underlie the different...Ch. 12.1 - Prob. 1TYKCh. 12.1 - The most common point of gene regulation in...Ch. 12.2 - Which genes are under the control of the lac...Ch. 12.2 - Prob. 2CCCh. 12.2 - Prob. 1BCCh. 12.2 - Prob. 1TYKCh. 12.3 - Prob. 1CCCh. 12.3 - Prob. 1TYKCh. 12.3 - Prob. 2TYK
Ch. 12.4 - Prob. 1CCCh. 12.4 - Prob. 1BCCh. 12.4 - A chromatin-remodeling complex may change the...Ch. 12.4 - Prob. 2TYKCh. 12.5 - What is the biological advantage of alternative...Ch. 12.5 - Prob. 2CCCh. 12.5 - Prob. 1TYKCh. 12.5 - Prob. 2TYKCh. 12 - Genes that are expressed at all times at...Ch. 12 - Prob. 2TYCh. 12 - Transcription factors that bind to DNA and...Ch. 12 - Prob. 4TYCh. 12 - Prob. 5TYCh. 12 - Prob. 6TYCh. 12 - Prob. 7TYCh. 12 - Prob. 8TYCh. 12 - Prob. 9TYCh. 12 - Prob. 10TYCh. 12 - What is the difference between inducible and...Ch. 12 - Transcriptional regulation often involves a...Ch. 12 - PRINCIPLES A principle of biology is that the...Ch. 12 - Discuss the advantages and disadvantages of...Ch. 12 - Prob. 2CBQ
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Describe how reversible chemical changes to histones are linked to chromatin modification.arrow_forwardDescribe how reversible chemical changes to DNA and histones are linked to chromatin modification.arrow_forwardTypically, increased acetylation and decreased methylation of histone N-terminal tails in nucleosomes leads to removal of the protein components of the chromatin from the DNA relaxed packaging of the chromatin and increased transcription increased amounts of euchromatin relative to heterochromatin activation of topoisomerase tighter packaging of the chromatin and reduced transcriptionarrow_forward
- Which of the following is likely to be transcriptionally expressed? euchromatin and DNA with methyl groups euchromatin DNA with methyl groups DNA with acetylated histones euchromatin and DNA with acetylated histonesarrow_forwardThe DNA-binding proteins that recognize and accurately initiate transcription at specific eukaryotic promoter sequences are called: chromatin-remodeling complexes. transcription factors. Enhancers. response elements.arrow_forwardDiscuss the levels of chromosomal organization with reference to the following terms: a. nucleotide b. DNA double helix c. histones d. nucleosomes e. chromatinarrow_forward
- Define about Chromatin Remodeling ?arrow_forwardHistones are: Group of answer choices Are present in eukaryotic, but not prokaryotic chromosomes All of these are true Have tails that can be modified and thereby change how actively a gene is transcribed Generally positively charged Are the protein components of nucleosomesarrow_forwardYou discover a histone variant that has more positive charge than conventional histone proteins. What effect do you predict this histone variant would have when it is inserted into chromatin? A decrease in the strength of histone-DNA interaction, making chromatin less condensed and increasing gene expression An increase in the strength of histone-DNA interaction, making chromatin less condensed and decreasing gene expression An increase in the strength of histone-DNA interaction, making chromatin more condensed and decreasing gene expression O A decrease in the strength of histone-DNA interaction, making chromatin less condensed and decreasing gene expressionarrow_forward
- Histones can be acetylated: acetyl (CH3CO) groups are attached to the amines. When it is time to transcribe DNA (to produce a needed protein), the histones need DNA-Protein Complexes Histones tightly bind to the DNA preventing transcription. to unwind from the DNA. histone protein nd u HN HN NH3 NH3 HN. H3N. -NH3 acetylation H3N- -NH3 H3N NH3 NH O NH3 NH Show why acetylation of the histone prevents it from interacting with DNA.arrow_forwardMethylated histone tail amino acids are associated with chromatin that is open only. closed only. about to replicate. either open or closed. newly replicated.arrow_forwardIf a section of a chromosome is heavily methylated, which of the following is likely to be true? Group of answer choices That portion of the chromosome is transcriptionally active That portion of the chromosome consists of euchromatin That portion of the chromosome is transcriptionally quiet RNA polymerase will have easy access to the DNA in that regionarrow_forward
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