What effect do you predict this histone variant would have when it is inserted into chromatin?

Histones contain many basic amino acids including lysine. DNA and histones collectively form chromatin. Open chromatin is much more open and accessible to the transcriptional machinery than closed chromatin. Histone lysine acetylation is associated with open chromatin and occurs near genes that are being actively transcribed. Part A Given what you know about the chemical properties of DNA and the function of histones. whv do histones contain so many basic amino acids? Answer in no more than two sentences. Part B Given what you know about how acetylation affects lysine, why does histone lysine acetylation open chromatin? Answer in one sentence only.

You have discovered a new species of plant. You isolate chromatin from the plant and examines it with the electron microscope and see characteristic beads on a string structure. After addition of a small amount of nuclease, which cleaves the string into individual beads that each contain 280 bp of DNA. With more digestion a 120-bp fragment of DNA remains attached to a core of histone protein. Analysis of the histone core reveals histones in the following proportions: H2A 33.3% H2B 33.3% H3 0% [no histone H3 found] H4 33.3% Based on these observations, what conclusions can you make about the probable structure of the nucleosome in the chromatin of this plant? Be specific in describing the nature of the nucleosome: which histones form the core (), how many of each are present () and size in bp of core-DNA that envelopes it ().

Which of the following statements most accurately represent chromatin state and transcription? Group of answer choices 1.Histone deacetylases promote closed chromatin and result in repressed transcription 2.Open chromatin is associated with hypoacetylation and has high levels of transcription 3.Histone acetyltransferases result in hypoacetylation and high levels of transcription 4.Hyperacetylation is associated with closed chromatin and low levels of transcription