Biology: Life on Earth with Physiology (11th Edition)
Biology: Life on Earth with Physiology (11th Edition)
11th Edition
ISBN: 9780133923001
Author: Gerald Audesirk, Teresa Audesirk, Bruce E. Byers
Publisher: PEARSON
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Chapter 11.3, Problem 1CSC

Sudden Death on the court

Many traits, in humans and other organisms, are inherited in a simple Mendelian fashion. Marfan syndrome, for example, is inherited as a dominant trait, which means that a single defective fibrillin allele is enough to cause the disorder. Flo Hyman inherited her defective allele from her father. Are all genetically determined traits inherited according to the straightforward patterns worked out by Gregor Mendel? Well return to this question in Section 11.5.

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Jekyll-Hyde Afflicted Spider Curse Afflicted Jekyll-Hyde/Spider Curse I O Human 1 II 1 III 4. Jekyll-Hyde disease is characterized by transformation into an unfeeling, aggressive, alter ego at night. While the "Spider Curse" is a disease that causes affected individuals to grow extra arms and extra eyes during a full moon. The genes responsible for these diseases sort independently and both traits run in one family. Based on the above pedigree answer the following questions: What is the mode of inheritance for Jekyll-Hyde disease? (Hint: look at individuals III-1 & III-3) O a. Autosomal Dominant O b. Autosomal Recessive O c. X-Linked Dominant O d. X-linked Recessive What evidence supports your hypothesis? Give at least 2 pieces of information from the pedigree that support your answer to 3a. Answer: 2. 3. 2. 2.
A couple enters your genetic counseling clinic for some family planning advice. The woman’s father was color blind, but her own vision is normal. The man has no family history of color blindness. Neither the man nor woman have any known history of hemophilia, but their first child (a boy) has hemophilia. They ask you to calculate the chance that their nextchild will be affected by one or both conditions. You remember from your genetics training that these are both X-linked recessive conditions and that they are closely linked: in fact, their genetic loci are separated by only 10cM! During the interview with this couple, you draw the following pedigree to represent their information. Given what you know, determine for this couple what chance they have of each of the following (in the table).
A couple is planning a family, but since each has a brother having the sickle-cell disorder, they are worried that their kids might develop the disorder too. Neither of them nor their respective parents have the disorder. Which of the following will be your smartest advice as a genetic counsellor?   One of four of their children can be expected to have sickle cell. It is possible that none of their kids will have the disorder, but tests should be carried out on both of them to confirm. All of their children will have sickle-cell disorder. There is no chance of any of their kids having sickle cell.

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Biology: Life on Earth with Physiology (11th Edition)

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