The effect of chemical modifications of histone proteins on nucleosome–DNA (deoxyribonucleic acid) interactions and gene activity. Introduction: Nucleosomes are the basic unit of packaging of the DNA molecule in eukaryotes. The nucleosome is folded in a successive ordered manner to form a chromosome. Nucleosome core particles consist of DNA molecules wrapped around the histone proteins. Histone protein is present as an octamer having two copies of each H2A, H2B, H3, and H4 in the core and a linker histone H1 that is associated with the linker DNA present between the two nucleosomes.

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Chapter 11, Problem 18PDQ

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The effect of chemical modifications of histone proteins on nucleosome–DNA (deoxyribonucleic acid) interactions and gene activity.

Introduction:

Nucleosomes are the basic unit of packaging of the DNA molecule in eukaryotes. The nucleosome is folded in a successive ordered manner to form a chromosome. Nucleosome core particles consist of DNA molecules wrapped around the histone proteins. Histone protein is present as an octamer having two copies of each H2A, H2B, H3, and H4 in the core and a linker histone H1 that is associated with the linker DNA present between the two nucleosomes.

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