BIOLOGY:THE ESSENTIALS (LL) W/CONNECT
BIOLOGY:THE ESSENTIALS (LL) W/CONNECT
3rd Edition
ISBN: 9781260670929
Author: Hoefnagels
Publisher: MCG CUSTOM
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Chapter 10.5, Problem 3MC
Summary Introduction

To determine:

The mechanism opted by biologists for using crossover frequencies to map genes on chromosomes.

Introduction:

Morgan, the famous scientist, presented his hypothesis which states that the recombinant offspring more likely to occur because crossing over often separates the alleles which are farther apart on chromosomes. Soon after Morgan’s hypothesis, Sturtevant, the student of Morgan, proposed mapping gene on the chromosome using crossing over frequency.

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In linkage mapping, how do we measure the distance between genes on a chromosome?  options:   A) The number of gametes used is proportional to the percent recombination in offspring.   B) The number of offspring produced is equal to the percent recombination during crossover.     C) The number of chromosomes resulting from crossover is equal to the distance the genes are apart in any one gamete.   D) The percentage of recombinant offspring is directly proportional to how far apart the genes are on the chromosome.
In a series of mapping experiments, the recombination frequencies for four different linked genes were     determined as follows: vg= vestigial wings   vg-b = 19 cn= cinnabar eyes    vg-cn = 9 rb= reduced bristles vg-rb = 16 b= black body           rb-b = 3.5                                     rb-cn = 6.5                                    cn-b = 9   Please map the genes in order on a chromosome.  Which two genes are the closest together? What is your evidence?
What is the main goal of comparative genome hybridization?Explain how the ratio of green to red fluorescence provides informationabout chromosome structure?

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BIOLOGY:THE ESSENTIALS (LL) W/CONNECT

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