Microbiology With Diseases By Taxonomy (6th Edition)
6th Edition
ISBN: 9780134832302
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Chapter 10, Problem 4SA
Summary Introduction
To determine:
The way in which antimicrobial agents that target protein synthesis is safe to use in humans.
Introduction:
The property of the antimicrobial agent to inhibit a pathogen is selective toxicity. All antimicrobial agents are selectively toxic to the pathogens so that they do not harm the host. Selective toxicity is expressed in the form of therapeutic dose to treat a disease and the dose at which the drug could become toxic to the host.
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Students have asked these similar questions
Important characteristics of antimicrobial drugs include:
a) readily delivered to the site of infection
b) high toxicity against microbial cells
c) do not cause serious side effects in humans
d) remains active in body tissues and fluids
e) all of the above
Which statement among A-D is false regarding bacterial toxins?
A) O Hemolysıns are cell membrane disrupters that can rupture red blood cells.
B) O Second mesengar pathway disrupters like cholera toxin produces a debilitating respiratory condition of the lungs.
C) O Shiga toxin, tetanus toxin, and hemolysins are all types of exotoxins.
D) O Superantigens elicit a hyperactive response by the immune system and can lead to shock.
E) O None are false, A-D are all true statements.
Which one of the following categories for antibacterial agents is most likely to have
toxic side effects for humans?
a) disruptors of cell membrane structure
b) inhibitors of cell wall synthesis
Oc) inhibitors of protein synthesis
d) antimetabolites
RESET
e) inhibitors of DNA synthesis
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Chapter 10 Solutions
Microbiology With Diseases By Taxonomy (6th Edition)
Ch. 10 - Prob. 1TMWCh. 10 - Some antimicrobial drugs are harmful to humans....Ch. 10 - Prob. 3TMWCh. 10 - Why is it incorrect to say that an individual...Ch. 10 - Prob. 1CCSCh. 10 - Prob. 1EDCSCh. 10 - Prob. 1MCCh. 10 - Prob. 2MCCh. 10 - Prob. 3MCCh. 10 - Which of the following statements is relevant in...
Ch. 10 - Prob. 5MCCh. 10 - Multiple-drug-resistant microbes _____. a. are...Ch. 10 - Prob. 7MCCh. 10 - Prob. 8MCCh. 10 - Prob. 9MCCh. 10 - What specific test for antimicrobial efficacy is...Ch. 10 - What characteristics would an ideal...Ch. 10 - Contrast narrow-spectrum and broad-spectrum drugs....Ch. 10 - Why is the fact that drug Z destroys the NAM...Ch. 10 - Prob. 4SACh. 10 - Prob. 6SACh. 10 - Prob. 7SACh. 10 - Prob. 8SACh. 10 - Compare and contrast the actions of polyenes,...Ch. 10 - Prob. 10SACh. 10 - Prob. 1CTCh. 10 - Prob. 2CTCh. 10 - Prob. 3CTCh. 10 - Prob. 4CTCh. 10 - Prob. 5CTCh. 10 - Even though aminoglycosides such as gentamicin can...Ch. 10 - Prob. 7CTCh. 10 - Prob. 8CTCh. 10 - Prob. 9CTCh. 10 - Antiparasitic drugs in the benzimidazole family...Ch. 10 - Prob. 11CTCh. 10 - Scientists have cultured bacteria isolated from...Ch. 10 - Prob. 14CTCh. 10 - Enterococcus faecium is frequently resistant to...
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- We have many antimicrobial drugs to treat bacterial infections, but very few for viruses. Why is it so difficult to treat viral infections? Hint: What would the targets for the drugs be?arrow_forwardWhat bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.arrow_forwardChanges in the bacterial genome can lead to resistance to antimicrobialdrugs. what the different ways that these changes in the DNA occur?arrow_forward
- Define antispasmodics.arrow_forwardThe type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicarrow_forwardWhich of the following statements about antibiotics is TRUE? a) Antibiotics are used to disinfect bench tops.b) An antibiotic is a type of antiseptic.c) Some antibiotics inhibit the growth of a pathogen and do not kill it.d) Some antibiotics work by binding the 40S ribosomal subunit.e) Antibiotics are used to treat fungal infections.arrow_forward
- The ribosome is the target for many important antibiotics. These drugs must discriminate between bacterial and eukaryotic ribosomes to achieve drug specificity and toxicity. For the two common antibiotics below, what is their mechanism of action and why are they more toxic to bacteria than eukaryotes? a) Tetracycline b) Erythromycinarrow_forwardwhy is peptidoglycan synthesis inportant in antibiotic activity? why do antibiotics not interfere with cell wall synthesis in the host cells?arrow_forwardAnswer all of the questions 1. Which of the following antimicrobial drugs target DNA/RNA synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 2. Which of the following antimicrobial drugs target protein synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 3. true or false: Streptococcus is killed by growing on blood agar.arrow_forward
- Many antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Tetracycline (ii) Puromycin (iii) Alpha-Amanitinarrow_forwardDescribe five modes of action for antibiotics. For each, provide one example.arrow_forwardMatch the PAMP to the type of pathogen it is specific to. 1) Peptidoglycan 2) Lipopolysaccharides 3) RNA 4) DNA Here is the options: a) Gram-negative bacteria b) Viruses c) Gram-positive bacteriaarrow_forward
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USMLE-Rx Antimicrobial Therapy; Author: USMLE-Rx;https://www.youtube.com/watch?v=Pka1Ynlrqtw;License: Standard Youtube License