Microbiology With Diseases By Taxonomy (6th Edition)
6th Edition
ISBN: 9780134832302
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Chapter 10, Problem 4CT
Summary Introduction
To determine:
The reason that why less than 1% of known antibiotics have practical value in treatment of disease.
Introduction:
The property of the antimicrobial agent to inhibit a pathogen is selective toxicity. All antimicrobial agents are selectively toxic to the pathogens so that they do not harm the host. The pathogens sometimes acquire resistance to one or more than one microbial agents.
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Below, you can see a picture of an antimicrobial drug. Regarding semi-synthetic antimicrobial drug development to try to avoid development of antibiotic resistance, use 1 sentence to address what is the significance/value of the presence of the various R-groups (e.g. R4, R5, R6, etc.)?
The reason why most antibiotics as oral suspension dosage forms are commercially available as dry powders, to be reconstituted with water just prior to dispensing, is:
What is a relevant biological process that can be used to briefly explain or illustrate the risks associated with antibiotics?
Chapter 10 Solutions
Microbiology With Diseases By Taxonomy (6th Edition)
Ch. 10 - Prob. 1TMWCh. 10 - Some antimicrobial drugs are harmful to humans....Ch. 10 - Prob. 3TMWCh. 10 - Why is it incorrect to say that an individual...Ch. 10 - Prob. 1CCSCh. 10 - Prob. 1EDCSCh. 10 - Prob. 1MCCh. 10 - Prob. 2MCCh. 10 - Prob. 3MCCh. 10 - Which of the following statements is relevant in...
Ch. 10 - Prob. 5MCCh. 10 - Multiple-drug-resistant microbes _____. a. are...Ch. 10 - Prob. 7MCCh. 10 - Prob. 8MCCh. 10 - Prob. 9MCCh. 10 - What specific test for antimicrobial efficacy is...Ch. 10 - What characteristics would an ideal...Ch. 10 - Contrast narrow-spectrum and broad-spectrum drugs....Ch. 10 - Why is the fact that drug Z destroys the NAM...Ch. 10 - Prob. 4SACh. 10 - Prob. 6SACh. 10 - Prob. 7SACh. 10 - Prob. 8SACh. 10 - Compare and contrast the actions of polyenes,...Ch. 10 - Prob. 10SACh. 10 - Prob. 1CTCh. 10 - Prob. 2CTCh. 10 - Prob. 3CTCh. 10 - Prob. 4CTCh. 10 - Prob. 5CTCh. 10 - Even though aminoglycosides such as gentamicin can...Ch. 10 - Prob. 7CTCh. 10 - Prob. 8CTCh. 10 - Prob. 9CTCh. 10 - Antiparasitic drugs in the benzimidazole family...Ch. 10 - Prob. 11CTCh. 10 - Scientists have cultured bacteria isolated from...Ch. 10 - Prob. 14CTCh. 10 - Enterococcus faecium is frequently resistant to...
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- The type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicarrow_forwardWhy are the risks associated with antibiotics hard to understand? Please describe in detail with reasoning in a supporting paragraph.arrow_forwardWhy is it better for a drug to be microbicidal than microbistatic?arrow_forward
- What is meant by ‘broad spectrum antibiotics’?arrow_forwardWhich of these antibiotics would do the best job as a broad spectrum antibiotic?arrow_forwardWhat is the main group of microorganisms producing the most antibiotics? Describe the biochemical characteristics of this microorganism and provide TWO (2) examples of antibiotics produced by these microbes.arrow_forward
- Which of the following statements about antibiotics is TRUE? a) Antibiotics are used to disinfect bench tops.b) An antibiotic is a type of antiseptic.c) Some antibiotics inhibit the growth of a pathogen and do not kill it.d) Some antibiotics work by binding the 40S ribosomal subunit.e) Antibiotics are used to treat fungal infections.arrow_forwardNo one would dispute the facts that the use of antibiotics is extremely beneficial. Why then are there currently discussions around the idea that we as a society should be limiting our antibiotic use? What are the pros and cons of utilizing antibacterial and antimicrobial products (NOT antibiotics) on a daily basis? Do you agree or disagree that the use of antibiotics should be reduced and if so, how should it be done?arrow_forwardExplain: 1. Pharmacokinetics of Unclassified Antibiotics 2. Pharmacodynamics of Unclassified Antibioticsarrow_forward
- We have many antimicrobial drugs to treat bacterial infections, but very few for viruses. Why is it so difficult to treat viral infections? Hint: What would the targets for the drugs be?arrow_forwardwhat are two broad classifications of antibiotics in terms of their ability to kill or inhibit?arrow_forwardSelective toxicity of a drug refers to a) damage to pathogenic organisms only b) damage to prokaryotic cell membranes c) damage to the target organisms but not the host cell d) easily broken down by the host and pathogen.arrow_forward
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