Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 10, Problem 2E

(a)

Summary Introduction

To calculate: The chemical potential difference for the given concentration values.

Concept introduction: The free energy change for moving a substance across a membrane depends upon the concentrations on both sides of the membrane. In case of ions, the free energy change depends upon the membrane potential. A random distribution of molecules is an energy-rich condition because when all the concentrations are equal, the free energy change is minimized. The difference in the concentrations of the substances on both sides of the membrane produces a potential difference called the chemical potential difference.

(b)

Summary Introduction

To calculate: The electrochemical potential for the given data, when the membrane potential is -60mV.

Concept introduction: The free energy change for moving a substance across a membrane depends upon the concentrations on both sides of the membrane. In case of ions, the free energy change depends upon the membrane potential. A random distribution of molecules is an energy-rich condition because when all the concentrations are equal, the free energy change is minimized. The difference in the concentrations of the substances on both sides of the membrane produces a potential difference called the chemical potential difference. The difference in the charge trans-membrane movement of ions across the membrane is called electrochemical potential.

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The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license