Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 10, Problem 20RQ
Many of the negative regulator proteins of the cell cycle were discovered in what type of cells?
- gametes
- cells in G0
- cancer cells
- stem cells
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Students have asked these similar questions
Which of the following statements is true regarding cell cycle regulators?
a. Cyclins determine which proteins each Cdks will act on.
b. Cdks check the DNA for damage and repairs it.
c. Cyclin binding to Cdks will result to Cdk inactivation.
d. Cyclin levels remain constant through the cell cycle.
Human cells divide every day for normal growth, replacement of cells, and tissue repair. The dividing cells proceed through the three phases of the cell cycle as shown in the figure. When a person experiences a cut, damaged skin cells secrete a protein called epidermal growth factor (EGF). Epidermal (skin) cells in the vicinity of the injury possess proteins in their cell membranes called epidermal growth factor receptors (EGFR)
Cancer can result from disruptions in cell cycle control. Mutations that increase the production of EGFR have been associated with skin cancer of the head and neck. Describe how a mutation outside of the coding region of a gene that encodes EGFR could lead to the overproduction of EGFR protein in a skin cell.
During interphase of the cell cycle, the chromosomes (DNA mass) of a cell _________.
decreases during S phase
increases (doubles) during the S phase
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decreases during G1
Chapter 10 Solutions
Biology 2e
Ch. 10 - Figure 10.6 Which of the following is the correct...Ch. 10 - Figure 10.13 Rb and other proteins that negatively...Ch. 10 - Figure 10.14 Human papillomavirus can cause...Ch. 10 - A diploid cell has ________ the number of...Ch. 10 - An organism s traits are determined by the...Ch. 10 - The first level of DNA organization in a...Ch. 10 - Identical copies of chromatin held together by...Ch. 10 - S. Chromosomes are duplicated during what stage of...Ch. 10 - Which of the following events does not occur...Ch. 10 - The mitotic spindles arise from which cell...
Ch. 10 - Attachment of the mitotic spindle fibers to the...Ch. 10 - Unpacking of chromosomes and the formation of a...Ch. 10 - Separation of the sister chromatids is a...Ch. 10 - The chromosomes become visible under a light...Ch. 10 - The fusing of Golgi vesicles at the metaplhase...Ch. 10 - At which of the cell-cycle checkpoints do external...Ch. 10 - What is the main prerequisite for clearance at the...Ch. 10 - If the M checkpoint is not cleared, what stage of...Ch. 10 - Which protein is a positive regulator that...Ch. 10 - Many of the negative regulator proteins of the...Ch. 10 - Which negative regulatory molecule can trigger...Ch. 10 - are changes to the order of nucleotides in a...Ch. 10 - A gene that codes for a positive cell-cycle...Ch. 10 - A mutated gene that codes for an altered version...Ch. 10 - Which molecule is a Cdk inhibitor that is...Ch. 10 - Which eukaryotic cell-cycle event is missing in...Ch. 10 - FtsZ proteins direct the formation of a...Ch. 10 - Compare and contrast a human somatic cell to a...Ch. 10 - What is the relationship between a genome,...Ch. 10 - Eukaryotic chromosomes are thousands of times...Ch. 10 - Briefly describe the events that occur in each...Ch. 10 - Chemotherapy drugs such as vincristine (derived...Ch. 10 - Describe the similarities and differences between...Ch. 10 - List some reasons why a cell that has just...Ch. 10 - What cell-cycle events will be affected in a cell...Ch. 10 - Describe the general conditions that must be met...Ch. 10 - Compare and contrast the roles of the positive...Ch. 10 - What steps are necessary for Cdk to become fully...Ch. 10 - Rb is a negative regulator that blocks the cell...Ch. 10 - Outline the steps that lead to a cell becoming...Ch. 10 - Explain the difference between a proto-oncogene...Ch. 10 - List the regulatory mechanisms that might be lost...Ch. 10 - ______ can trigger apoptosis if certain cell-cycle...Ch. 10 - Name the common components of eukaryotic cell...Ch. 10 - Describe how the duplicated bacterial chromosomes...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Chromosomes are duplicated during what portion of the cell cycle? a. G 1 phase b. S phase c. prophase d. prometaphasearrow_forwardIn the cell cycle, at which stages do two chromatids make up one chromosome? a. beginning of mitosis b. end of G1 c. beginning of S d. end of mitosis e. beginning of G2arrow_forwardA tumor suppressor protein, p21, inhibits Cdk1. The earliest effect p21 on the cell cycle would be to stop the cell cycle at: a. early G1. b. late G1. c. the S phase. d. G2. e. the mitotic prophase.arrow_forward
- Cells that DO NOT divide or participate in the cell cycle are usually arrested in what phase? a. S phase b. Prophase c. G2 d. G0 e. M phasearrow_forwardPassage of cells from G1 through R to S depends on the interaction of various signal molecules, proteins and enzymes which regulate the cell cycle. Imagine I have just induced a mutation in a cell line which prevents the breakdown of the cyclin molecule we discussed. Which of the following events do you predict will happen? circle all that apply Select one or more: a. Uncontrolled cell replication may result b. Retinoblastoma protein will be continuously active c. The cells will be stuck in G1 phase d. The cells will begin to replicate their DNA e. Cyclin dependent kinase (Cdk) will be continuously activearrow_forwardHow does MPF trigger M phase of the cell cycle? A. MPF phosphorylates proteins that triggers the activation of M phase B. MPF has a regulatory role in breakdown of the nuclear envelope during M phase C. MPF is a dimer subunit that is turned on during S phase to aid with chromosome replication D. MPF Cdk subunits regulate M phasearrow_forward
- Scientists are able to isolate cells in various phases of the cell cycle. During an experiment in which Dr. Patrick McGroyn is causing cultured tumor cells to go through mitotic cell division, he isolates a group of cells that contain one and a half times more DNA than cells isolated in the G1 phase have. What phase must these cells be in? How do you know?arrow_forwardSometimes a cells "deal with" damaged DNA by just killing off the cell. This special cellular suicide is called apoptosis. Usually, the cell cycle has checkpoints that prevent damaged/mutated cells from proceeding to the next phase, though. When these checkpoints don't work, apoptosis can be used. If apoptosis did NOT occur, how might the damaged DNA impact the rest of the cell cycle? A. it may not complete the cell cycle correctly B. new cells containing damaged DNA may be made C. the cell may enter G0 D. all of the above are options E. A and B, but not C F. B and C, but not Aarrow_forwardIn the diagram, the speed bumps (look like short walls) represent __________. A) The only times at which genes may be actively expressed B) Points in time when the cell divides C) One-hour timepoints D) Checkpoints in the cell cycle .arrow_forward
- In which stage of the eukaryotic cell cycle is the genetic material properly referred to as chromatin?A. during the G2 phase onlyB. during the G1 phase onlyC. during the M phase onlyD. during the S phase onlyE. during interphase onlyarrow_forwardWhich of the following would be expressed at varying levels during different parts of the cell cycle? A. cyclin-dependent kinases B. RNA polymerase C. cyclins D. Glycolysis enzymesarrow_forwardWhich phase of the cell cycle is depicted in this diagram? a) S phase b) early prophase c) metaphase d) G1 phasearrow_forward
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