Scientists are able to isolate cells in various phases of the cell cycle. During an experiment in which Dr. Patrick McGroyn is causing cultured tumor cells to go through mitotic cell division, he isolates a group of cells that contain one and a half times more DNA than cells isolated in the G1 phase have. What phase must these cells be in? How do you know?

Scientists are able to isolate cells in various phases of the cell cycle. During an experiment in which Dr. Patrick McGroyn is causing cultured tumor cells to go through mitotic cell division, he isolates a group of cells that contain one and a half times more DNA than cells isolated in the G1 phase have. What phase must these cells be in? How do you know?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter2: Cells And Cell Division

Section: Chapter Questions

Problem 18QP: How can errors in the cell cycle lead to cancer in humans?

See similar textbooks

Similar questions

1) Examine the picture of an onion root tip with cells in various stages of the cell cycle. A student claims that interphase is the longest stage of the cell cycle. Another student claims that mitosis is the longest stage. Using evidence from the photo, determine which student is correct and why. A) Mitosis is the longest stage because anaphase requires more time to separate chromatids. B) Interphase is the longest stage because chromosomes are visible in the majority of the cells. C) Mitosis is the longest stage because the majority of the cells in the photo are replicating their DNA. D) Interphase is the longest stage because the majority of the cells in the photo have uncondensed chromatin and are not dividing. Not Graded
If you were to look at a sample of “normal” cells, what phase of the cell cycle do you think most of the cells would be in? If you were to look at a sample of cancer cells, what phase of the cell cycle do you think most of the cells would be in?
3) Examine the graph showing the relative percentage normal and cancer cells spend in various stages of the cell cycle. Based on the information in the graphs, infer how cancer cells differ from typical, noncancerous cells. Select ALL that apply. A) Cancer cells do not replicate their DNA. B) Cancer cells replicate their DNA too quickly. C) Cancer cells do not go through interphase during their cell cycle. D) Cancer cells spend more time dividing compared to typical cells. E) Cancer cells do not always grow to the same size as typical cells. more than 1 answer. not graded
Examine the picture of an onion root tip with cells in various stages of the cell cycle. A student claims that interphase is the longest stage of the cell cycle. Another student claims that mitosis is the longest stage. Using evidence from the photo, determine which student is correct and why A)mitosis is the longest stage because anaphase requires more time to separate chromatids B) interphase is the longest stage because chromosomes are visible in the majority of the cells C) mitosis is the longest stage because the majority of the cells in the photo are replicating their dna D) interphase is the longest stage because the majority of the cells in the photo have uncondensed chromatin and are not dividing
4) Describe in detail how p53 and MDM2 regulate cell division in a normal, healthy cell. You should describe 1) how these proteins cooperate to allow a cell to go through the cell cycle, 2) how they cooperate to stop the cell cycle, and 3) how they allow the cell cycle to continue again after having stopped it initially. You may use point form if you want.
The interphase is the part of the eukaryotic cell cycle that is most transcriptionally active. Gene regulation during this phase involves changes in the chromatin. a) What is chromatin? b) How can the chromatin structure change?
Name the phases of the cell cycle. b) During which phases are the chromosomes and then the cytoplasm split, respectively? c) Describe one mechanism that is used to regulate the cell cycle.
If a mad scientist hands you a cell culture with 100 cells that just entered g1. He needs to extract the MOST possible DNA from 100 cells. On top of that, he requires that the DNA cannot be condensed. To accomplish this goal he gives you a set of chemicals that will stop a cell in any part of the cell cycle you want. What part of the cell cycle would you stop the cell at, that matches those requirements?
The cell cycle control system is a cycling set of molecules in the cell that triggers and coordinates key events in the cell cycle. This is all controlled by growth factors. a) Identify the major checkpoints in a cell and its function. b)Explain the role of the growth factor.
Cell division cycle mutations render the mutants unable to continue the cell cycle. This phenotype creates a paradox where mutant cells must also be grown in the lab to further identify the gene and study the role of the protein. How do you think this problem can be solved?
One important biological effect of a large dose of ionizing radiation (like X-rays) is to halt cell division. How does this occur? To answer this question, state the name and role of 2 specific and important proteins involved in the process. What happens if a cell has a mutation that prevents it from halting cell division after be irradiated? Be specific and detailed. An adult human who has reached maturity will die within a few days of receiving a radiation dose large enough to stop cell division. What does that tell you about cell division? In addition, name 2 different/unique cell types that would be primarily affected.
In class, we talked about flow cytometry which allows scientists to determine what stage of the cell cycle cells are in by measuring their DNA content. Draw what the graph would look like for the mutant below at a 0-time point when there are 1000 cells total, with 5000 cells in G1, 350 cells in M and G2, and 150 cells in S phase. And then a graph of 1 hour later when the cells should have competed for mitosis: → loss of function of cdc25