Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 1, Problem 3P
The size of one copy of the human genome is approximately 3 billion base pairs, and it contains about 25,000 genes organized into 23 chromosomes.
| a. | Human chromosomes vary in size. What would you predict is the size of the average chromosome? |
| b. | Assuming that genes are spread evenly among chromosomes, how many genes does an average human chromosome contain? |
| c. | About half of the DNA in chromosome contains genes. How large (in base pairs) is an average human gene? |
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The size of one copy of the human genome is approximately 3 billion base pairs, and it contains about 27,000 genes organized into 23 chromosomes,
a. Human chromosomes vary in size. What would you predict is the size of the average chromosome?
The size of one copy of the human genome is approximately 3 billion base pairs, and it contains about 27,000 genes organized into 23 chromosomes.
Human chromosomes vary in size. What would you predict is the size of the average chromosome?
Assuming that genes are spread evenly among chromosomes, how many genes does an average human chromosome contain?
The size of one copy of the human genome is approximately 3 billion base pairs, and it contains about27,000 genes organized into 23 chromosomes.a. Human chromosomes vary in size. What wouldyou predict is the size of the average chromosome?b. Assuming that genes are spread evenly amongchromosomes, how many genes does an averagehuman chromosome contain?c. About half of the DNA in chromosomes containsgenes. How large (in base pairs) is an averagehuman gene?
Chapter 1 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 1 - Choose the phrase from the right column that best...Ch. 1 - If one strand of a DNA molecule has the base...Ch. 1 - The size of one copy of the human genome is...Ch. 1 - Indicate whether each of the following words or...Ch. 1 - a. How many different DNA strands composed of 100...Ch. 1 - Why do scientists think that all forms of life on...Ch. 1 - Why would a geneticist study a yeast cell or a...Ch. 1 - How can a scientist tell if a protein present in...Ch. 1 - Why do scientists think that new genes arise by...Ch. 1 - Explain how the exon/intron structure of genes...
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- A diploid human cell contains approximately 6.4 billion base pairs of DNA. a. How many nucleosomes are present in such a cell? (Assume that the linker DNA encompasses 40 bp.) b. How many histone proteins are complexed with this DNA?arrow_forwardA typical eukaryotic chromosome found in humans has about 100 million bp of DNA. As noted in Chapter 11, 1 DNA base pair has a linear length of 0.34 nm.A. What is the linear length of the DNA in a typical human chromosomein micrometers?B. What is the linear length of a 30-nm fiber of a typical humanchromosome?C. Based on your calculation in part B, would a typical human chromosome fit inside the nucleus (with a diameter of 5 μm) if the 30-nm fiber were stretched out in a linear manner? If not, explain how a typical human chromosome fits inside the nucleus during interphase.arrow_forwardCell (A) contains 3.1 billion (3.1 x 109) base pairs of DNA. Each nucleosome has about 200 bp of DNAwrapped around the histone core.a. What is the maximum number of nucleosomes that can be present in the cell?b. What is the maximum number of H2A histone protein molecules that can be present in the cell?arrow_forward
- If an average length of the double helix DNA in a dwarf coconut is 197.538 cm and one full turn of a typical DNA has ten base pairs with a length of 3.4 nm: How many base pairs would be present in such a chromosome? Show your solution. If the average length of all the chromosomes of a dwarf coconut is 197.538 cm in length, how many base pairs would be present in a coconut embryo? Show your solution.arrow_forwardA diploid human cell contains approximately 6.4 billion base pairs of DNA. Assuming that the linker DNA encompasses 35 bp, how many nucleosomes are present in such a cell? Use two significant figures. How many histone proteins are complexed with this DNA? use two significant figures.arrow_forwardCertain organisms contain cells that possess polytene chromosomes. What are polytene chromosomes, where are they found, and what function do they serve?arrow_forward
- A typical eukaryotic chromosome found in humans contains about100 million bp. one DNA base pair has alinear length of 0.34 nm.A. What is the linear length of the DNA in a typical human chromosome in micrometers?B. What is the linear length of a 30-nm fiber of a typical humanchromosome?C. Based on your calculation in part B, would a typical humanchromosome fit inside the nucleus (with a diameter of 5 µm) ifthe 30-nm fiber was stretched out in a linear manner? If not,explain how a typical human chromosome fits inside thenucleus during interphase.arrow_forwardThe human genome is approximately 3 billion basepairs in size.a. Using standard 8.5″ × 11″ paper with one-inch margins, a 12-point font size, and single-spaced lines, howmany sheets of paper printed on one side would berequired to print out the human genome?b. A ream of 500 sheets of paper is about 5 cm thick.How tall would the stack of paper with the entirehuman genome be?c. Would you want a backpack, shopping cart, or asemitrailer truck to haul around this stack?arrow_forwardThe average human chromosome contains about 1 x 108 bp of DNA.(a) If each base pair has a mass of about 660 daltons and there are about 2 g of protein (histones plus nonhistones) per gram of DNA, how much doessuch a chromosome weigh (in grams)?(b) If the DNA were extended, how long would it be?(c) An actual chromosome is about 5 mm long. What is the approximatecompaction ratio?(d) You have about 4 x 1012 cells in your body. If you have 46 chromosomes in each cell, what is the approximate extended length of all of your DNA? For comparison, the distance from the earth to the sun isabout 1.5 x 108 km.arrow_forward
- A compact disc (CD) stores about 4.8 × 109 bits of information in a 96 cm2 area. This information is stored as a binary code—that is, every bit is either a 0 or a 1. how many bits would it take to specify each nucleotide pair in a DNA sequence? how many CDs would it take to store the information contained in the human genome?arrow_forwardThe human genome (3.4 Gb) would be 2.3 metres long if stretched linearly. In not more than 200 words, explain how a genome of this size is fit into a cell of minuscule proportions. You may add a diagram to your answer.arrow_forwardThe average human chromosome contains about 1 x 108 bp of DNA. (a) If each base pair has a mass of about 660 daltons and there are about 2 g of protein (histones plus nonhistones) per gram of DNA, how much does such a chromosome weigh (in grams)? (b) If the DNA were extended, how long would it be? (c) An actual chromosome is about 5 mm long. What is the approximate compaction ratio? (d) You have about 4x 1012 cells in your body. If you have 46 chromosomes in each cell, what is the approximate extended length of all of your DNA? For comparison, the distance from the earth to the sun is about 1.5x108 km.arrow_forward
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Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License