Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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You discover a new antibiotic that inhibits translation. Upon futher investigation, you find that the antibiotic binds to the A site of the ribosome. What process of translation will most likely be inhibited?
Termination
Elongation
Initiation
Assembly
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Introduction :-
Elongation is the second phase of protein synthesis (translation), during which the ribosome moves along the mRNA molecule in a 5' to 3' direction, adding one amino acid at a time to the growing polypeptide chain
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- compare and contrast the initiation process for transcription and translation. what similarities and differences are there?arrow_forwardWhat type of the mRNA is recognized as a first step of translation initiation in eukaryotes? a TaTA sequence A shine dalgarno sequence the 7- methylguanosine cap the start codonarrow_forwardWhy do ribosomes move along mRNA during translation?arrow_forward
- You are treating a patient suffering with wound botulism in which Clostridium botulinum grows in a wound and makes a protein exotoxin, botulinum toxin. In addition to surgery to clean the wound and providing botulinum antitoxin, you wish to give the patient antibiotics to stop the protein toxin synthesis immediately. Which of the following antibiotics would you NOT give your patient if you wished to immediately stop bacterial translation? (best answer) O macrolides, e.g. erythromycin O trimethoprim plus sulfa drugs e.g. sulfamethoxazole O chloroamphenicol tetracylines aminoglycosides e.g. gentamicinarrow_forwardWhen translation begins, the first amino acid heads to the small subunit of the ribosome. What brings the amino acid there, and why does it interact with that specific part of the mRNA?arrow_forwardFind the events from prokaryotic translation from the list below and list them below in order, by letter, from earliest to latest during translation A. Incoming tRNA occupies the A-site B. Small ribosome binds to Shine Dalgarno sequence C. 5’ methyl cap binds small ribosome D. Large ribosome subunit binds the small ribosome subunit E. P-site tRNA peptide is attached to the amino acid of the A-site tRNA. F. f-Met tRNA binds to P site G. Small ribosomal subunit binds mRNA H. Peptide released from complex.arrow_forward
- In the initiation of translation, the process always lines up at the start codon. What is the start codon? _______ What does the initiator tRNA do? The subunits of the ______________ then bind together around the mRNA and initiator tRNA.arrow_forwardWhich eukaryotic initiation factor (elF) brings the initiator tRNA to the ribosome? 0 0 0 elF1 elF3 elF4arrow_forwardWhich of the following is NOT a protein that aids the ribosome during translation?Question 28 options: A) charging factor B) initiation factor C) release factor D) elongation factorarrow_forward
- Describe the difference in translation initiation between prokaryotes and eukaryotes.arrow_forwardAll of the following statements about translation are true except: Release factors recognize stop codons and prompt-cleavage of a peptide bond. Initiation factors are involved in ribosome assembly. In prokaryotes, initiator transfer RNA (tRNAf) is attached to formylmethionine. Each messenger RNA contains a start codon and a stop codon.arrow_forward
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