YOU ARE WORKING WITH A NEW DRUG TO TREAT BREAST TUMORS.  PRESENT AN OUTLINE OF THE STEPS YOU WOULD CARRY OLUT IN PRECLINICAL TESTING.  WHAT ASPECTS OF DRUG ACTIVITY AGAINST THE TUMOR CAN BE ADDRESSED: IN MONOLAYER CULTURE? IN MUTICELLULAR TUMOR SPHEROID CULTURE? WHAT TYPES OF COMPLEX TISSUE CULTURE ENVIRONMENTS MAY ALSO BE USEFUL FOR DRUG TESTING?

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Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.