Write a balanced equation for the hydrolysis of cGMP, catalyzed by cGMP phosphodiesterase. Would you expect an inhibitor of this enzyme to potentiate or antagonize the action of Viagra? Explain.

Explain why people with a hereditary deficiency of carnitine acyltransferase II have muscle weakness. Why are the symptoms more severe during fasting?

Answer the following questions about the inhibition of acetylcholine esterase by neostigmine. 5a. Does neostigmine have a structure that enables it to bind reversibly to the ACbE active site? 5b. Is neostigmine catalytically processed by ACHE? 5c. How does the stability of the carbamolyl-enzyme intermediate produced by treatment of ACbE with neostigmine compare to the stability of the acetyl- enzyme intermediate produce when ACb, is hydrolyzed?

Write the sequence of steps for the biosynthesis of phosphatidylcholine by the salvage pathway from oleate, palmitate, dihydroxyacetone phosphate, and choline. Name the enzyme for each step.

In the regulation of glycogen phosphorylase, which of the following statements is true? The inactive T form becomes activated when it gets dephosphorylated. The active R form is inhibited by glucose. Phosphoprotein phosphatase catalyzes the attachment of a phosphate group to a Ser residue in glycogen phosphorylase. The allosteric modulator glucose-6-phosphate promotes the conformation change from inactive T state to active R state.

In Cyclooxygenase (COX) Inhibitors, how is prostaglandin synthesis; what are the mechanism of action for COX inhibitors; and compare and contrast COX-1 versus COX-2 selective inhibitors.

Briefly explain....Represent the reactions when Phosphatidylethanolamine was treated with; (I) Phospholipase C (ii) Phospholipase D

Name two conditions in which the enzymes involved in the TCA cycle might be inhibited.

Can you answer all the parts to this question please List effectors of glycogen phophorylase: A. When blood [glucose] is high. B. When blood [glucose] is low.