With respect to glycogen, what is the likely fate of excess glucose 6-phosphate in muscle?

What is the physiologic significance of pyruvate dehydrogenase complex?What's the biochemical basis for the management of diabetes mellitus and contrast glucose homeostasis in neonates and adults.

Which of the following is the correct summary of the anaerobic breakdown of glucose in the skeletal muscle?   Glucose + ADP + Pi ⟶ lactate + ATP   Glucose + 2ADP + 2Pi ⟶ 2 lactate + 2ATP   Glucose + 2ADP + 2Pi + 2NAD+ ⟶ 2 pyruvate + 2ATP + 2NADH + 2H+   Glucose + ADP + Pi ⟶ pyruvate + ATP   Glucose + 2ADP + 2Pi ⟶ 2 pyruvate + 2ATP

it is known that exercise is good for diabetics. explain how GLUT 4 transporters may be involved in this beneficial effect of exercise.

Hexokinase deficiency (HKD) is a congenital disease that can disrupt intracellular glucose levels. Please provide an explanation of the diseases impact on intracellular glucose levels and the mechanism by which how GLUT1 regulates this disrupted glucose level.

A 16-year-old female is recently diagnosed with a deficiency of muscle glycogen phosphorylase. She and her family are concerned and ask the following questions. Based on what you know about skeletal muscle glycogenolysis and muscle metabolism, please respond to each question with a thoughtful answer that describes the metabolism in these various scenarios in language that your patient will understand, while also being sure to include the role of the relevant metabolic pathways, specific enzymes, and stimulus for their activity: I’m not sure I understand the issue. Can you explain how muscle glycogen is used normally during exercise?  I really like to take long walks; will Istill be able to do this with my friends?  As a result of this deficiency, will I need to get up at night to eat to maintain my blood glucose levels?  Do I need to worry about producing excessive lactate during intense anaerobic exercise?

Under FASTING state, how do the hormonal changes bring about the effect to maintain glucose homeostasis in the body through the pathways of GLYCOLYSIS and GLUCONEOGENESIS; GLYCOGENOLYSIS and GLYCOGENESIS? (Please describe the signaling pathways in detail. )

Glycogen synthase in the liver is a target for phosphorylation by two protein kinases. What are these two protein kinases and how are they independently regulated by glucagon and insulin to regulate glycogen biosynthesis?

Which of the following conditions is most likely to force a muscle cell to metabolize glucose anaerobically(fermentation) under normal oxygenation ? - Glyceraldehyde-3-phosphate dehydrogenase deficiency - Lactate dehydrogenase deficiency  -Pyruvate kinase deficiency  -Aldolase deficiency  - Cytososic Glycerol-3-phosphate dehydrogenase deficiency

What factors affect the rate of glycogen synthesis following depleting exercise, and what steps can we take to maximize glycogen restoration?