Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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- You discover a new species of poison-dart frog which secretes a neurotoxin in the skin mucous with LD50 of 0.5 mg/kg in humans. The toxin causes numbness, paralysis, arrhythmias, cardiac failure, and death. Based on the patch-clamp record of inward currents when the neurotoxin was applied to squid axon shown in Figure 2, suggest the mechanism of action of the neurotoxin. 500 PA 5 ms Figure 2 (Source: Google image)arrow_forwardD Question 13 Immediately after an action potential has peaked, which cellular gates open? O calcium O chloride Osodium Opotassium < Previousarrow_forwardOn the graph above, when do the sodium ion channels close? Select one: a. between 0.2 ms and 0.5 ms, which is when depolarization occurs b. at 0.2 ms, which is when depolarization occurs c. at 0.5 ms, which is when repolarization begins d. between 0.5 ms and 0.8 ms, which is when repolarization occursarrow_forward
- At the membrane of an axón, the action potential is -60 mV for K+ ions. Calculate de external and internal concentration radios.arrow_forwardShown attached are the recordings from one cell in the Swimmy CPG circuit. The first recording is under controlconditions, when the fish is swimming normally. The second recording is of the same neuron when every othercell in the CPG is hyperpolarized and not firing. The large black bars have been placed at the first spike in thecontrol condition. Which of the following can you conclude about this cell from the data shown below? Make sure to choose the most complete answer. a. This cell is tonically active.b. This cell is an endogenous burster cellc. This cell is an endogenous burster cell that is normally acted on by at least one inhibitory synapse.arrow_forwardWhat enables action potential to jump from one node of Ranvier to the next? A. Increased LC B. Increased membrane resistance OC. Decreased LC OD. A and B OE. B and C mmmmmarrow_forward
- Extracellular recordings create a distinct action potential. Choose the option that best describes the trace recording after stimulation. 1.The voltage trace becomes increasingly positive because the extracellular space becomes less negative 2.The voltage trace becomes increasingly positive because the extracellular space becomes less positive 3.The voltage trace becomes increasingly negative because the extracellular space becomes less positive 4.The voltage trace becomes increasingly negative because the extracellular space becomes more positivearrow_forwardThe plasma membrane of the giant squid axon becomes depolarized in response to action potential. true falsearrow_forwardConduction velocity refers to the [a] at which an action potential travels along a neuron's axon. In invertebrates, conduction velocity can only be increased by [b]. However in vertebrates (exclusively), such as humans, conduction velocity can also be increased by [c]. This enables vertebrates to conserve [d] while still increasing conduction velocity. [a] [b] [c] [d] [Choose ] [Choose ] [Choose ] [Choose ]arrow_forward
- What drives K+ ions through voltage gated channels while funny channels are also open? O pifference in K+ concentration across the PM O pressure potential O Both difference in K+ concentration across the PM and Membrane potential (difference in charge across the membrane) O Osmotic potential O Membrane potential (difference in charge across the membrane)arrow_forwardGive typed full explanationarrow_forwardName the following ion channels are sensitive to pressure waves in fluid of the inner ear? voltage-gated channels ligand-gated channels with extracellular ligands potassium channels at the Nodes of Ranvier ligand-gated channels with intracellular ligands stress-activated channelsarrow_forward
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