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Which treatment would eliminate the early inward current in a squid giant axon? O Applying a calcium channel blocker Removal of external potassium Removal of external sodium O Applying a potassium channel blocker

Which treatment would eliminate the early inward current in a squid giant axon? O Applying a calcium channel blocker Removal of external potassium Removal of external sodium O Applying a potassium channel blocker

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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### Understanding Early Inward Current in Squid Giant Axons The squid giant axon is a well-studied model in neuroscience, and understanding the mechanisms involved in generating electrical signals is critical. The early inward current is a vital part of the action potential, primarily carried by sodium ions entering the cell. This educational resource explores the impact of various treatments on this early inward current. #### Quiz Question: **Which treatment would eliminate the early inward current in a squid giant axon?** 1. Applying a calcium channel blocker 2. Removal of external potassium 3. Removal of external sodium 4. Applying a potassium channel blocker ### Explanation of Options: - **Applying a calcium channel blocker:** Calcium channels are less involved in the early phases of the action potential in squid giant axons; hence, blocking these channels would not significantly impact the early inward sodium current. - **Removal of external potassium:** External potassium primarily affects the repolarization phase of the action potential. Its removal would influence the late current and not the early inward sodium current. - **Removal of external sodium:** The early inward current is predominantly carried by sodium ions. Removing external sodium would eliminate this current because there would be no sodium influx to initiate the depolarization phase of the action potential. - **Applying a potassium channel blocker:** Potassium channels contribute to repolarization and the maintenance of resting membrane potential. Blocking these channels would not directly impact the early inward sodium current. ### Correct Answer: **Removal of external sodium** By understanding these treatments, students can appreciate the specific roles of different ions and channels in nerve signal transmission, particularly in the context of the squid giant axon model.
Transcribed Image Text:### Understanding Early Inward Current in Squid Giant Axons The squid giant axon is a well-studied model in neuroscience, and understanding the mechanisms involved in generating electrical signals is critical. The early inward current is a vital part of the action potential, primarily carried by sodium ions entering the cell. This educational resource explores the impact of various treatments on this early inward current. #### Quiz Question: **Which treatment would eliminate the early inward current in a squid giant axon?** 1. Applying a calcium channel blocker 2. Removal of external potassium 3. Removal of external sodium 4. Applying a potassium channel blocker ### Explanation of Options: - **Applying a calcium channel blocker:** Calcium channels are less involved in the early phases of the action potential in squid giant axons; hence, blocking these channels would not significantly impact the early inward sodium current. - **Removal of external potassium:** External potassium primarily affects the repolarization phase of the action potential. Its removal would influence the late current and not the early inward sodium current. - **Removal of external sodium:** The early inward current is predominantly carried by sodium ions. Removing external sodium would eliminate this current because there would be no sodium influx to initiate the depolarization phase of the action potential. - **Applying a potassium channel blocker:** Potassium channels contribute to repolarization and the maintenance of resting membrane potential. Blocking these channels would not directly impact the early inward sodium current. ### Correct Answer: **Removal of external sodium** By understanding these treatments, students can appreciate the specific roles of different ions and channels in nerve signal transmission, particularly in the context of the squid giant axon model.
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