Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Which statement below best describes what these data might have demonstrated to Kornberg
about the process of replication? CHOOSE ONE and explain the rationale behind your
answer in a minimum of four sentences.
A. Products of replication are DNA polymers .
B. DNA Pol I-mediated replication is a high-fidelity (i.e., no mistakes) process
C. DNA Pol III-mediated replication gives rise to two daughter strands, one which is made of only the
original templates, and one of which is only newly synthesized polymer.
D. In DNA, all 4 classes of nitrogenous bases are more or less equally represented
E. A pairs with T and C pairs with G
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- A drug that inhibits the DNAa protein is added to a culture of E. coli cells. What is the first step of DNA replication that will be impaired by this drug? PICK ONE ANSWER: A. Keeping parent DNA strands separated B. Releasing tension generated by supercoiling C. Activating the origin of replication D. Making primers E. Forming phosphodiester bondsarrow_forwardThere are 2 parts to this question: The following DNA strand (below) is about to undergo DNA replication. a) Please replicate the parental strands into two exact copies TC GATATCGG AGCTATAGCC b) place a centromere between the two replicated copies (or tell me where the centromere would be located),arrow_forwardWhat is the real definition of DNA ligase to make it truearrow_forward
- Which of the following DNA double helices would be more difficultto separate into single-stranded molecules by treatment withheat, which breaks hydrogen bonds?A. GGCGTACCAGCGCATCCGCATGGTCGCGTAB. ATACGATTTACGAGATATGCTAAATGCTCTExplain your choice.arrow_forwardDescribe the main jobs of each of the following enzymes in the E. coli model of replication: A. DNA Polymerase I B. DNA Polymerase II C. DNA Polymerase IIIarrow_forwardGive detailed Solution with explanation (don't give Handwritten answerarrow_forward
- Even though the eukaryotic genome is thousands of times larger than the prokaryotic genome, DNA replication times are relatively similar. Explain how this is possible.arrow_forwardWhich of the following types of DNA damage would be hardest to repair using the DNA repair pathways?A. Complete removal of three nucleotides in the middle of one strand.B. A covalent bond between a base on one strand and a base on the complementary strand.C. Incorporation of a sugar other than deoxyribose into one strand.D. Covalent attachment of a short polypeptide to a single base.E. A covalent bond between a base and a deoxyribose on the same strand. Please explain why it's Barrow_forwardOnly typed explanationarrow_forward
- Describe three (3) effects on DNA replication if DNA polymerase could build DNA in both directions – in both the 5’ to 3’ direction and the 3’ to 5’ direction.arrow_forwardConsider a DNA molecule with the following structure a. if during replication , the T at position 4 is read as an A resulting in a misincorporation in the new DNA strand . If the misincorporation is not repair , draw or write the results of the second round of replication b. After the second round of replication , what specific type of point mutation is now permanent in the DNA sequence ? c. List the two cellular mechanisms that failed to prevent the establishment of this permanent mutation .arrow_forwardHow do you fill out this table?arrow_forward
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