Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Which region of eukaryotic DNA prevents single-strand breaks and chromosome unraveling, and serves as a signal to DNA repair enzymes that the linear chromosome does not need repairing?
- the centromere
- the terminator
- the promoter
- the telomere
- the operator
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- DNA polymerase occasionally incorporates the wrong nucleotide during DNA replication. If left unrepaired, the base-pair mismatch that results will lead to mutation in the next replication. As part of a template strand, the incorporated wrong base will direct the incorporation of a base complementary to itself, so the bases on both strands of the DNA at that position will now be different from what they were before the mismatch event. The MER-minus strain of yeast does not have a functional mismatch excision repair system, but it has normal base excision repair and nucleotide excision repair systems. Which of the following statements is correct about differences in the mutation spectrum between MER-minus and wildtype yeast? More than one answer is correct. Options: More point mutations will arise in MER-minus yeast. Fewer point mutations will arise in MER-minus yeast as compared with wildtype. Of the total point mutations that…arrow_forwardThe diagram below shows a nucleosome with DNA (wire structure) wrapped around the outside. Where would you look for the Histone Code? 3 2 region 4 region 2 O region 1 O region 3arrow_forwardIn eukaryotes, why is less DNA transcribed the more it is compactedarrow_forward
- Histones are: Group of answer choices Are present in eukaryotic, but not prokaryotic chromosomes All of these are true Have tails that can be modified and thereby change how actively a gene is transcribed Generally positively charged Are the protein components of nucleosomesarrow_forward. Which structure in the eukaryotic chromosome is about 700-840 nm in diameter, contains scaffold proteins, lamins, and topoisomerases, in addition to histone proteins, and is transcriptionally silent? the radial minibands the solenoid the nucleosome naked DNA the euchromatinarrow_forwardThe mismatch DNA repair mechanism is based on the fact that: O a. O b. O C. O d. The parental DNA strand is recognized because it is structurally distorted. The parental DNA strand is methylated while daughter strand is not. The daughter DNA strand is recognized because it is structurally distorted. The daughter DNA strand is methylated while parental strand is not.arrow_forward
- . Which structure in the eukaryotic chromosome is about 2 nm in diameter, contains no histone proteins associated with double-stranded DNA, and is easily accessible to transcription? the heterochromatin the nucleosome the solenoid the naked DNA the radial minibandsarrow_forwardPut the following steps of transcription in orderarrow_forward
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