Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
Which of these happens to acetyl•CoA in the mammalian liver?
It can be converted to
It can give rise to glucose through gluconeogenesis.
It can be used in the pentose phosphate pathway to produce NADPH.
It can be oxidized to CO2 for energy production by the citric acid cycle.
It can be converted to cholesterol via the isoprenoid pathway.
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- Which of the following is NOT a regulatory mechanism for catabolism and anabolism? Phosphorylation of enzymes in glycogenesis and glycogenolysis Modulation of enzymes in glycolysis and the aerobic stage of cellular respiration by intermediates and products of the pathway Conversion of pyruvate to alanine Differences in enzymatic activities in response to variations in the concentration of substrates Activation of gluconeogenesisarrow_forwardWhich enzyme in ß-oxidation extracts two electrons from the fatty acid, resulting in the eventual generation of 1.5 ATP each time that it catalyzes a reaction? O Acyl-CoA dehydrogenase O succinate dehydrogenase O L-hydroxyacyl-CoA dehydrogenase O Enoyl-CoA hydratasearrow_forwardThe metabolic function of the pentose phosphate pathway is: act as a source of ADP biosynthesis provide intermediates for the citric acid cycle. generate NADPH and pentoses for the biosynthesis of fatty acids and nucleic acids. O participate in oxidation-reduction reactions during the formation of H2O.arrow_forward
- Which of the following conditions is most likely to lead to the activation of pyruvate dehydrogenase? High concentrations of acetyl-CoA High concentrations of NADH High concentrations of NAD+ High concentrations of CO2arrow_forwardWhich of the following Krebs cycle enzymes generates a molecule of FADH2 from FAD? a-ketoglutarate dehydrogenase pyruvate dehydrogenase isocitrate dehydrogenase malate dehydrogenase succinate dehydrogenasearrow_forwardWhen proteins are digested for fuel, they are first broken down into their amino acid components. Amino acids can be further oxidized to generate useful energy for the cell. For example, when one molecule of the amino acid tryptophan is oxidized, one pyruvate molecule and one acetyl CoA molecule are generated. One NADH molecule is also generated during the oxidation of tryptophan into one pyruvate molecule and one acetyl CoA molecule. Below is the general reaction described in the prompt: 1 tryptophan --> 1 pyruvate + 1 acetyl CoA + 1 NADHarrow_forward
- in the mitochondria pyruvate is converted into acetyl CoA so then acetyl CoA make its way to the TCA cycle and produces energy sources for oxidative phosphorylation. Pyruvate oxidation transforms pyruvate, a three-carbon molecule, into acetyl, a two-carbon molecule linked to Coenzyme A, generating NADH and releasing one carbon dioxide molecule in process the citric acid cycle is fundamental because runs on acetyl CoA as its fuel. i need more explanantionarrow_forwardwhat metabolic process is this, and why?arrow_forwardWhich of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinasearrow_forward
- Which citric acid cycle enzyme utilizes a similar reaction mechanism to pyruvate dehydrogenase? O Malate dehydrogenase Isocitrate dehydrogenase O Alpha-ketoglutarate dehydrogenase Succinate dehydrogenasearrow_forwardWhich of the following glycolytic enzymes must consume ATP during phosphorylation of its preferred substrate molecule? phosphoglycerate mutase pyruvate kinase succinate dehydrogenase hexokinase phosphoglycerate kinasearrow_forwardWhen acetyl-CoA containing radioactively labeled carbon atoms is fed to cells, the CO, produced is not initially radioactive. However, molecules of citrate and oxaloacetate are radioactive. Only after some time has passed will radioactive CO2 be released. What is the best explanation for this observation?arrow_forward
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