Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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- Before a fatty acid can undergo B-oxidation it must be: O Transport of the FA into the mito. matrix O Hydrolysis of the carboxyl group from the FA O Carboxylation of Acetyl-CoA to form malonyl-CoA Activation of the FA with Coenzyme A O Oxidation of the FA yielding a A2-enoyl intermediatearrow_forwardWhat is incorrect in the diagram shown below? Mall-com Thiolysis SCOA + H₂S-Co COA Acetyl CoA Acetyl CoA H₂C The products should be acetyl CoA and propionyl CoA. Sulfur should not be present in any molecular structure. Acyl group cleavage occurs in a different step of the B-oxidation pathway. The B-oxidation pathway directly generates ATP, which is not shown here.arrow_forwardHow many times does stearic acid (CH3(CH2)16COOH) spiral through the β@oxidation pathway to produce acetyl-CoA?arrow_forward
- Which of the following is TRUE? O Both AMP and ADP are negative regulators of glycogenolysis. ATP shifts the curve of glycogen phosphorylase to the left. O Citrate binds covalently to acetyl CoA carboxylase. Phosphofructokinase-1 is an allosterically regulated enzyme in glycolysis. The carnitine shuttle is positively regulated by Malonyl CoA.arrow_forwardWhich of the following is an important enzyme involved in the synthesis of cholesterol from isoprene pyrophosphate? thiolase pyruvate decarboxylase pyruvate dehydrogenase HMG-CoA reductase glucose oxidasearrow_forwardwhat is the relationship between the pairs in the following analogy. :chocolate: cookie as cheese: hamburgerarrow_forward
- How many of each of these molecules are produced in the complete beta-oxidation of one 10-carbon fatty acid molecule? acetyl-CoA molecules: NADH molecules: 5 Incorrect FADH₂ molecules: 5 5 Incorrectarrow_forwardWhich of the following Krebs cycle enzymes generates a molecule of FADH2 from FAD? a-ketoglutarate dehydrogenase pyruvate dehydrogenase isocitrate dehydrogenase malate dehydrogenase succinate dehydrogenasearrow_forwardwhat metabolic process is this, and why?arrow_forward
- Which of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinasearrow_forwardWhat enzyme(s) is/are specifically required for the oxidation of a Aeven monounsaturated fatty acid? (select all that apply) O Methylmalonyl CoA Mutase O enoyl-CoA Hydratase 43-enoyl-CoA isomerase Thiolase 2,4-Dienoyl-CoA Reductase OPropionyl-CoA carboxylasearrow_forwardHow many acetyl-CoA molecules can be produced from a 20-carbon chain free fatty acid?arrow_forward
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