Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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- Hac1 is another chaperone protein that is up-regulated in response to unfolded proteins in the ER. You detect amounts of Hac1 mRNA and protein in the absence and presence of unfolded protein in the ER of a eukaryotic cell as shown in the figure below. b. Describe two specific biological processes that the cell could regulate in order to increase the amount of Hac1 protein. Briefly explain your answer using the information from figure C & D. Hac1 MRNA expression Hac1 protein expression Unfolded proteins in ER No unfolded No unfolded proteins In ER Unfolded protelns in ER proteins in ERarrow_forwardIn addition to euchromatin and general transcription factors, initiation of transcription in humans requires __________ in proximal promoters and activators bound to __________. Question 2 options: No 5-methylcytosine; distal promoter but not proximal promoter No 5-methylcytosine; both distal promoter and proximal promoter 5-methylcytosine; distal promoter but not proximal promoter 5-methylcytosine; both distal promoters and proximal promoters No 5-methylcytosine; proximal promoter but not distal promoterarrow_forwardA lake with low nutrient levels and very clear water is called eutrophic oligotrophic a dead zone a septic zone oxygen depletedarrow_forward
- If a mutation occurred in a control element sequence associated with a particular gene, which of the following would be a likely consequence of this? A. This mutation is not likely to affect the expression of the associated gene, because RNA polymerase does not bind to control elements. B. This will likely affect the expression of the associated gene because it will loosen the coiling of chromatin at this site. C. The expression of the associated gene will be affected because this change will result in a nonsense mutation. D. This mutation is not likely to affect the expression of the associated gene, since control elements are noncoding sequences. E. The associated gene's expression would likely be affected, since this mutation would change the ability of at least one transcription factor to bind.arrow_forwardControl of gene expression in eukaryotic cells occurs at which level(s)? Lüffen birini seçin: a. epigenetic and transcriptional levels O b. post-transcriptional, translational, and post-translational levels O c. only the transcriptional level O d. epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels O e. epigenetic, transcriptional, and translational levelsarrow_forwardHow is the expression of genes controlled at the chromosomal level? A. DNA can synthesize extra histones as needed B. DNA can either be condensed into heterochromatin or decondensed into euchromatin C. DNA can be unwound into euchromatin to reduce the level of expression D. The expression of DNA can only be controlled at the transcriptional level E. DNA is spontaneously deleted from a chromosome if not neededarrow_forward
- In eukaryotes, chromatin remodeling plays an important role is gene regulation. This is because a. repositioning of the nucleosomes makes DNA accessible to transcription regulatory proteins b. the nucleosomes contain important regulatory regions c. chromatin remodeling activates gene expression d. chromatin remodeling represses gene expressionarrow_forwardLet's say there is an eukaryotic gene that has five exons and 4 introns. If the GU sequence at the 5' splice site of the third intron is deleted, describe how this is going to affect the expression of this gene. draw the mature mRNA too.arrow_forwardWhy must chromatin be remodeled at a eukaryotic promoter? Histone proteins must be added to the promoter so they can recruit RNA polymerase II Histone proteins are blocking promoter sequences recognized by general transcription factors (GTFs) Space needs to be made for the ribosome to bind to a nascent (i.e. newly transcribed) mRNA Because enhancer regions need to be exposed for general transcription factor binding To allow the spliceosome to remove exons from the mRNA during transcriptionarrow_forward
- If an organism's cells were to not want a specific sequence of DNA transcribed for a long period of time, which of the following processes below would most likely allow for this to happen? O DNA acetylation O DNA methylation O histone methylation O histone acetylationarrow_forwardYou are studying how gene expression is regulated in the cell. For gene z, you find that while there are high levels of mRNA in the cell, there are low levels of the protein encoded by gene z. Describe a regulatory mechanism that could explain this finding that occurs after translation.arrow_forwardTranscription in prokaryotic cells O A. is initiated at a promoter and uses only one strand of DNA (the template strand) to synthesize a complementary RNA strand. B. occurs in the nucleus, whereas translation occurs in the cytoplasm. C. is terminated at a stop codon. D. does not need a promoter. O E. is initiated at a start codon with the help of initiation factors and the small subunit of the ribosome. 5arrow_forward
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