Which of the following is NOT a signal molecule? А. САМР В. GABA C. Insulin D. Glucagon E. Acetylcholine

Which of the following is incorrect about protein kinase A (PKA)? a. It is activated by the 2nd messenger b. None; all the other choices are correct C. It has catalytic and regulatory subunits Od. Phosphorylations catalyzed by PKA can be reversed by protein phosphatases

You are seeking a new anti-inflammatory drug to inhibit local responses to stress and injury. Which of the following activities would you look for in a potential anti-inflammatory agent? A It should function as a dominant-negative receptor for pro-inflammatory cytokines. It should be an agonist of a pro-inflammatory cytokine. C It should compete with the pro-inflammatory cytokine for the binding to its receptor. D It should function as a constitutively active receptor for pro-inflammatory cytokines. E It should facilitate the production of second messengers in response to a pro-inflammatory cytokine.

xytocin stimulates contraction of smooth muscles in the breast and uterine wall. The key step in muscle contraction is release of calcium from internal cell stores. With which type of receptor does oxytocin interact to cause muscle contraction?   A. Gαi-coupled receptor   B. Tyrosine kinase coupled receptor   C. Cytokine type 1 receptor   D. Ser/Thr kinase receptor   E. Gαq-coupled receptor

Psilocybin is rapidly de-phosphorylated in the body into psilocin, which is anagonist For the 5-HT 24 Serotonin receptor, which binds the neurotransmitter serotonin as its natural ligand, and acts as a ligand-gated ion channel in the central nervous system. НО. Serotonin NH₂

Hydrophobic signaling molecules act by a. binding to plasma proteins b. starting second messenger systems c. binding to receptors inside the cell d. starting action potentials

Regulatory molecules (enzymes, 2nd messengers & effectors) influenced by G-protein systems: YOU CAN CHOOSE MORE THAN 1  A.adenylyl cyclase B.phospholipase c C.ion channels (Ca2+, K+) D.protein kinases

Which of the following is a secondary messenger?   a. cyclic AMP (cAMP)     b. phosphorus         c. glucose   d. sodium

Which of the following would inhibit the activity of TGF-Beta receptor? multiple answers    A. Deletion of Extracellular domain   B. Tyrosine Kinase Inhibitor   C. Mutation that prevents homodimerization of Type II Receptor   D. Mutation of phosphorylation site on Type I receptor   E. Inhibition Type II receptor binding to Type I receptor

Testerone is a steriod (lipid) hormone. Which of the following would be the most likely receptor for this hormone? Select one: a. A transmembrane receptor in the cell membrane since it cannot diffuse across the cell membrane b. An intracellular receptor because it can diffuse across the cell membrane