When ethanol binds to glutamate receptors it operates as a receptor ______________________ and prevents cellular _________________________. A. agonist / depolarization B. antagonist / hyperpolarization C. antagonist / depolarization D. agonist / hyperpolarization
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When ethanol binds to glutamate receptors it operates as a receptor ______________________ and prevents cellular _________________________.
- A. agonist / depolarization
- B. antagonist / hyperpolarization
- C. antagonist / depolarization
- D. agonist / hyperpolarization
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- The drug Buckeyium binds to the NMDA receptor at the orthosteric binding site (were glutamate would normally bind). Assume that glycine is already bound, and that magnesium is not blocking the NMDAR ion channel. If the channel does not open as a result of Buckeyium binding than Buckeyium would be considered a ____________. A. Indirect Antagonist B. Positive Allosteric Modulator C. Negative Allosteric Modulator D. None of the choice options are correct E. Non-Competitive AntagonistWhich second messenger pathway enzyme is used with alpha-2 adrenergic receptors? A. phosphodiesterase (PDE) B. adenylate cyclase C. ATP hydrolaseSelect All statements that are TRUE regarding the effects of administering a molecule that is a precursor for the synthesis of a neurotransmitter A. Temporarily compensate for neuron cell death by increased release of the neurotransmitter (ex. L-dopa used as treatment for Parkinson’s disease) B. Increase the rate of synthesis of that neurotransmitter C. Block the reuptake of the neurotransmitter back into the axon terminal D. Immediately alter then number of postsynaptic receptors E. Act as an indirect antagonist by activating autoreceptors
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- What are the neurotransmitters that bind to ionotropic channels and allow for cation influx? Select all that apply. Group of answer choices A. glutamate B. GABA C. dopamine D. acetylcholineFill in the blank: _______________________ are receptors that are sensitive to changes in the concentrations of chemicals.Cocaine affects a synapse by blocking the reuptake or reabsorbtion of the neurotransmitter dopamine by the presynaptic neurons. Therefore,the levels of dopamine continue to build in the synapse, causing certain effects on the body. A. Explain how cocaine interferes with neural transmission across the synapse B.Describe the natural role of dopamine in the brain C. Predict how cocaine could be addictive after only one use.
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