Which of the following is associated with active chromatin? Check all that apply. A. Centromeres B. heterochromatin C. histone acetylation D. Polytene puffs E. metaphase chromasomes F. transcription of machinery

Which of the following is associated with active chromatin? Check all that apply. A. Centromeres B. heterochromatin C. histone acetylation D. Polytene puffs E. metaphase chromasomes F. transcription of machinery

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter10: Cell Division And Mitosis

Section: Chapter Questions

Problem 1ITD: Biologists have long been interested in the effects of radiation on cells. In one experiment,...

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Concept explainers

Oogenesis

The formation of the ovum (mature female gamete) from undifferentiated germ cells is called oogenesis. This process takes place in the ovaries (female gonads). Oogenesis consists of three stages known as the multiplication phase, growth phase, and maturation phase.

Cell Division

Cell division involves the formation of new daughter cells from the parent cells. It is a part of the cell cycle that takes place in both prokaryotic and eukaryotic organisms. Cell division is required for three main reasons:

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The conversion of euchromatin into heterochromatin involvesa. the formation of more nucleosomes.b. the formation of less nucleosomes.c. a greater compaction of loop domains.d. a lesser compaction of loop domains.e. both a and c.
Loosening the chromatin structure occurs because of Select one: a. Lysine methylation b. Lysine acetylation c. Lysine phosphorylation d. Lysine sumoylation
Which of the following statements most accurately represent chromatin state and transcription? Group of answer choices 1.Histone deacetylases promote closed chromatin and result in repressed transcription 2.Open chromatin is associated with hypoacetylation and has high levels of transcription 3.Histone acetyltransferases result in hypoacetylation and high levels of transcription 4.Hyperacetylation is associated with closed chromatin and low levels of transcription
Histones form more accessible chromatin because of Select one: a. Reduced electrostatic attraction between the histone and the negatively charged DNA backbone b. Increased electrostatic attraction between the histone and the negatively charged DNA backbone c. Reduced covalent bonding between the histone and the negatively charged DNA backbone d. Increased covalent bonding between the histone and the negatively charged DNA backbone
Which of the following statements is NOT true about chromatin architecture? A. The histone tails on heterochromatin are deacetylated B. Heterochromatin is heavily methylated C. Euchromatin is more likely to contain genes that are expressed at that time D. Euchromatin is heavily methylated
Give at least one example of a chromosomal structureor function affected by the following mechanisms formodulating chromatin structure:a. Posttranslational changes of the normal histonesfound in the nucleosome
Which of the following statements correctly describes the structure of chromatin around the promoter of an active eukaryotic gene? O A. It is in the form of heterochromatin and the nucleosomes are tightly wrapped. O B. It is in the form of euchromatin and the nucleosomes are cleared from the region allowing for an open and accessible configuration OC.A repressor protein is bound to the chromatin blocking RNA polymerase. O D.Both B and C.
A cell is homozygous for a LOF mutation in the histone acetyltransferase (HAT) gene. Which of the following is/are true? a. Chromatin in the cell will be more condensed than usual, decreasing expression of genes that should be expressed. b. This will lead to histones with more positive charges on their tails, increasing the interaction between histones and the DNA backbone. c. This will lead to a decrease in DNA methylation and therefore cause an increase in gene expression. d. Chromatin in the cell will be less condensed than usual, increasing expression of genes that should not be expressed.
Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to Select one: a. inhibition of DNA synthesis. O b. myosin denaturation and inhibition of cleavage furrow formation. c. suppression of cyclin production. Od. inhibition of regulatory protein phosphorylation. O e. disruption of mitotic spindle formation. Next page
Which of the following is a type of chromatin remodeling? O the changing of amino acid sequence of histones the changing of chromatin binding sites in the genome O the changing of nucleosome position the changing of nucleotide sequences of the genome
Changes in chromatin packing correlate with changes in gene expression in most cells. Why do you think this is the case?
Describe the mechanism by which histone modifications are established after DNA replication and cell division. What are some things that could go wrong if modifications can't be maintained? Think about what histone modifications do to DNA and why cells maintain parts of their chromosome as heterochromatin.