Which of the following is associated with a decrease in cell-cell interactions? Select one: a. loss of MMPs b. loss of basement membrane proteins c. increased integrin expression d. Loss of integrins e. loss of E-cadherin

Which of the following is associated with a decrease in cell-cell interactions? Select one: a. loss of MMPs b. loss of basement membrane proteins c. increased integrin expression d. Loss of integrins e. loss of E-cadherin

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter9: Cell Communication

Section: Chapter Questions

Problem 1VCQ: Figure 9.8 HER2 is a receptor tyrosine kinase. In 30 percent of human breast cancers, HER2 is...

See similar textbooks

Related questions

Q: A mutation that knocks out the GTPase activity of a G protein would have what effect on a cell? a.…

A: (a) G protein would always be active

Q: Which of the following is a change to the CdK/cyclin system that could result in cell division…

A: There are two types of cell division: mitosis and meiosis. Mitosis is the equational division in…

Q: sequences from deleterious mutations. D. These regions may contain regulatory sequences that control…

A: Mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during…

Q: Which of the following are methods of cellular signaling? Select one: a. All the answers are…

A: Cellular signaling is a process of communication or passing form one cell to another by signaling…

Q: After the initial Actualization of the Cit+ phenotype, there was another alteration to the A-3…

A: Bacteria are dynamically evolving microbes. Various experiments suggest the evolution process of…

Q: a. A typical cellular response of a mammary epithelial cell to EGF signal is proliferation. the Kd…

A: Proliferation is the cellular response.

Q: ne epidermal growth factor receptor (EGFR) activates a complex signaling network - increase…

A: The example shown in the question shows the ligand binding and the cascading of effects that is…

Q: What is the main benefit of cell signaling via direct physical contact and cell signaling over short…

A: Cell signaling over a short distance is also called local signaling and it includes paracrine and…

Q: Why do signaling responses that involve changesin proteins already present in the cell occur in…

A: Signaling responses that involve changes in proteins already present in the cell occur in…

Q: Please choose one of these choices A. Since protein A is embedded in the membrane., the mutation…

A: Mutations are changes in the sequence of DNA which may or may not affect the structure of proteins.

Q: Which of the following elements may be in the transduction part of cell signaling? Select one: a.…

A: Ans: Signal transduction: The process of transporting signal from cells exterior to the internal is…

Q: The following figure shows how the activities (y-axis) of Cdk-Cyclin B complex and the APC complex…

A: * Mitosis is type of cell division where cell divides into two which gives genetically identical…

Q: which condition a trimeric G protein is activated by a cell-surface receptor, a. the a subunit…

A: The answer to this question is given below,

Q: The following images represent confocal images of cells with full-length Mira protein (Mira 1-830),…

A: Confocal microscopy creates an image of a specimen by filtering out the out-of-focus light coming…

Q: Based on the information scientists and doctors have been able to collect, compare embryonic stem…

A: Embryonic stem cells are derived from preimplantation embryos (inner cell mass) and iPSCs are…

Q: What is the main benefit of cell signaling over long distances (ex: signaling via hormone secretion…

A: Cell signaling is the essential cycle by which explicit data is moved from the cell surface to the…

Q: A researcher studying a line of cancer cells noticed that cellular content of RhoBTB3 and Cyclin E1…

A: The cell cycle includes events that terminates with the division of cells. The division process is…

Q: Describe how Ras and p53 can alter the simplified genetic pathway controlling cell division shown…

A: There are two general types of genes that play a fundamental role in cancer induction:…

Q: One of the key components in vertebrate limb development is the polarizing region, also known as…

A: Introduction :- Undifferentiated mesenchyme is enveloped by an ectoderm layer in the limb bud. The…

Q: What would be the likely result of a mutation of the bcl-2 gene on the level of apoptosis? a. No…

A: Answer: Introduction: Bcl-2 (B-cell lymphoma 2), occurred in humans produced by the BCL2 gene, this…

Q: A mutation in Ras that prevents Ras from hydrolyzing GTP. Would cause? Why? A. Increased…

A: To produce many diploid cell progeny, cell proliferation is achieved by combining cell growth with…

Q: Microtubules are important for transporting cargo in nerve cell axons, as diagrammed in Figure Q17-…

A: Introduction The cytoskeleton mostly consists of microtubules. They are present in every eukaryotic…

Q: There is now significant evidence to support the existence of cytoneme-mediated delivery of…

A: Cytoneme: it is signalling filopodia that provide conduit for spatial distribution of morphogen.…

Q: Which of these processes is MOST directly involved in the resorption of a tadpole’s tail during…

A: The process of resorption of tale in tadpoles is one of the most physiologically notable processes…

Q: Describe an example of a pathological condition that results in mutants genes that control…

A: Inducing Facto Signal Transduction Pathway and Components ssociated Pathogen Developmental Functions…

Q: Why would a mutation in BRCA1 be considered a driver mutation? b. Based on what you’ve learned…

A: In this question, we have to answer 'BRCA gene consider as driver mutation and ATM consider as a…

Q: you drew plant cells and you may have noticed that the cells appear rectangular or square in shape.…

A: plant cells are usually rectangular or square shaped and have a well defined and rigid struture ,…

Q: Describe and connect five different outcomes that could occur due to the loss of FMRP function in…

A: The FMRP protein is made using instructions from the FMR1 gene. The brain, testes, and ovaries are…

Q: Glucocorticolds are steroid hormones that are released into the circulation and will cause changes…

A: The correct option is C

Q: Which statement is not true about G proteins? A. They are integral membrane proteins. B.…

A: G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as…

Q: Consider the nature of cell signaling pathway outcomes. Which of the following is a benign mutation…

A: The correct option is C Results in increased p53 Activity. explanation In a normal cell there are…

Q: What are the 4 key signalling cues communicated within a cell to regulate cellular behaviour.

A: NOTE:- "As you have posted two questions under one, we will solve the first part for you, to get the…

Q: Scaffold proteins (a) release kinases and phosphatases into the extracellular fluid (b) bind G…

A: Scaffold proteins play critical roles in many key flagging pathways. Despite the fact that…

Q: The receptor-associated proteins called G proteins... A. bind GTP. B. can activate or inhibit an…

A: G-proteins are associated with G-protein coupled receptors (GPCRs). GPCR is a seven transmembrane…

Q: When the gene encoding a certain cellular kinase is deleted, the resulting mutant cells arrest in…

A: Answers : fusion protein are the proteins which are synthesized in the laboratory for the…

Q: a) What you can expect for gene α regulation by this ligand? What signaling mechanism could be used?…

A: Cell signal involves three major steps- 1) binding of extracellular signaling molecules (ligands) to…

Q: hat are cyclins and cyclin-dependent kinases for? Describe how do these factors affect cell…

A: A cell is a basic membrane-bound unit that is frequently referred to as the basic building blocks of…

Q: If there is a mutation in importin that prevents it from interacting with the NLS of cargo proteins,…

A: Importin is a protein that transports various substances to nucleus via nuclear localization signal.…

Q: Which of the following does not apply to a transmembrane receptor? a. It lacks ER signal sequence.…

A: Answer : b. It contains one or more hydrophobic stop-transfer sequence

Q: Listeria is a type of bacteria that can infect human cells leading to the activation of the…

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: Which could lead to uncontrolled growth in cancer? A. A nonfunctional E2F protein B. The…

A: a)A nonfunctional E2F protein: False E2F is a transcription factor that is the principal target of…

Q: n order for certain cancers to propagate, they require a growth factor known as Vascular Endothelial…

A: Introduction:- VEGF A chemical produced by cells that promotes the creation of new blood vessels.…

Q: Which of the following would most likely reduce levels of active estrogen to potentially modulate…

A: Introduction Estrogens are a class of hormones that plays a vital function in women's sexual and…

Q: Over-expression of the bcl-2 gene in a cell is likely to be associated with .. a) an increased…

A: A protein that helps govern whether a cell lives or dies by preventing the cell death process known…

Q: You have developed an activator of a non-receptor tyrosine kinase. In three different cell types…

A: A subset of the protein family of tyrosine kinases, enzymes that can shift the phosphate group to a…

Q: What two steps occur in cell signaling occur AFTER the signal has been detected by a cell surface…

A: Receptors are usually proteins , which are present on the cell membrane, which binds to the ligand…

Q: Why do cancer cells undergo EMT and MET? What are the cellular changes (expression or suppression of…

A: Answer

Concept explainers

Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.

Question

Which of the following is associated with a decrease in cell-cell interactions?

Select one:

loss of MMPs

loss of basement membrane proteins

increased integrin expression

Loss of integrins

loss of E-cadherin

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.

Similar questions

Many common medications function by interrupting the normal operation of certain signal transduction pathways. Which of the following describes a possible mechanism by which a certain medication may interrupt a signal transduction pathway? A A medication enters the target cell and triggers apoptosis by causing the release of di- gestive enzymes from cell lysosomes. B A medication interacts with the phospholipid bi-layer of the cell membrane and in- creases its permeability. с D A medication binds to membrane-bound glucose proteins and acts as an allosteric in- hibitor that prevents the intake of glucose by the cell. A medication diffuses through the membrane of a target cell and inhibits an enzyme that normally synthesizes a second messenger.
RAS is a signal transducer that acts as a switch for turning on cell division. Drag the descriptions below to their proper places on the figure to show the sequence of events. When growth factor binds to the receptor, the intracellular domain activates RAS by facilitating exchange of GDP for GTP. When no growth factor is bound to the extracellular receptor, RAS is bound to GDP and is inactive. RAS activates the first of three sequential kinase proteins termed the MAP kinase cascade. Cell proliferation proceeds as the machinery for cell division is set in motion. The end result of the MAP kinase cascade is activation of a transcription factor. Receptor 1 Ras GDP 2 4 5 Growth factor Ras GTP
Define Integrin adhesion receptor– mediated signaling pathways control diverse cell functions.
A cell begins to undergo apoptosis due to stress. Which of the following are true about this cell? (select all that apply) The cell can exit apoptosis if the stressful factor is removed The cell has high levels of p53. The cell's DNA will inevitably degrade The cell may undergo mitosis before completing apoptosis
Figure 9.8 HER2 is a receptor tyrosine kinase. In 30 percent of human breast cancers, HER2 is permanently activated, resulting in unregulated cell division. Lapatinib, a drug used to treat breast cancer, inhibits HER2 receptor tyrosine kinase autophosphorylation (the process by which the receptor adds phosphates onto itself), thus reducing tumor growth by 50 percent. Besides autophosphorylation, which of the following steps would be inhibited by Lapatinib? Signaling molecule binding, dimerization, and the downstream cellular response. Dimerization, and the downstream cellular response. The downstream cellular response. Phosphatase activity, dimerization, and the downsteam cellular response.
Which of the following changes to the microtubule binding protein, Tau, commonly occurs in Alzheimerâ s and other neurodegenerative diseases? A Tau is hypo-phosphorylated and does not bind to microtubules to destabilize them. B Tau levels are so low in the cell that they only bind to some microtubules. C Tau is hyper-phosphorylated and does not bind to microtubules to stabilize them. D Microtubules are hyper-phosphorylated and do not bind to Tau.
Illustrate a complete cell signaling cascade from signal to response. Each protein in the pathways must be shown. You can choose either a GPCR or an RTK mediated pathway.
Which of the following modifications of the Epithelial Growth Factor Receptor (EGFR) would be proliferative of epithelial cells? multiple answers A. Mutation of active site residue responsible for tyrosine phosphorylation. B. Deletion of extracellular ectodomain C. Mutation in ectodomain that prevents binding of EGF D. Cell expresses EGF E. Mutation in promoter that increases expression of EGF receptor F. Dimerization of receptor without growth factor G. Mutation in EGFR promoter that decreases expression of receptor
Imagine that there is a mutation in the SRP receptor that disrupts its function. What is the logical outcome of this? Select all statements below that are true. Oa. SRP will no longer bind to the signal peptide O b. Membrane protein insertion will no longer occur correctly O c. SRP will no longer bind the SRP receptor O d. Vesicular movement from the ER to Golgi is inhibited O e. Proteins are no longer able to enter the secretory system
Predict the effects of the following mutations on the ability of a cell to undergo apoptosis:a. Mutation in Bad such that it cannot be phosphorylated by protein kinase B (PKB)b. Overexpression of Bcl-2c. Mutation in Bax such that it cannot form homodimersOne common characteristic of cancer cells is a loss of function in the apoptotic pathway. Which of the mutations listed above might you expect to find in some cancer cells?
The epidermal growth factor receptor (EGFR) activates a complex signaling network to increase expression of several genes and promote cell proliferation as shown in the figure below. EGF Active EGFR Inactive EGFR Inactive EGFR P- EP Inactive Ras-GDP Ras-GTP Active Raf -P NUCLEUS МЕК-F МАРК-Р Active МАРК-P C-myc gene transcribed CYTOPLASM Cell proliferation Which of the following scenarios would result in decreased expression of the c-myc gene? Select all that apply A homozygous mutation of the EGFR gene resulting in a deletion of the ligand binding domain A homozygous mutation of the ras gene so that Ras protein was not able to exchange GDP for GTP A homozygous mutation of the ras gene so that Ras protein was not able to hydrolyze GTP for GDP A homozygous mutation of the MAPK gene so that MAPK protein was always in a phosphorylated state
Describe three ways in which the response of a cell to asignal can be terminated.