Which of the following epidermal growth factor (EGF) receptors cannot bind ligands but will form heterodimers with other EGFs? O HER2 (mouse Erb2) O HER3 (mouse Erb3) O HER1 (mouse Erb1) O HER4 (mouse Erb4)

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Which of the following epidermal growth factor (EGF) receptors cannot bind ligands but will form heterodimers
with other EGFs?
O HER2 (mouse Erb2)
HER3 (mouse Erb3)
O HER1 (mouse Erb1)
O HER4 (mouse Erb4)
Transcribed Image Text:Which of the following epidermal growth factor (EGF) receptors cannot bind ligands but will form heterodimers with other EGFs? O HER2 (mouse Erb2) HER3 (mouse Erb3) O HER1 (mouse Erb1) O HER4 (mouse Erb4)
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Epidermal growth factor (EGF) is a protein that plays a key role in the regulation of cell growth, proliferation, and differentiation. It is a member of the EGF family of growth factors that includes several other proteins with similar structures and functions. EGF acts by binding to and activating its receptor, the epidermal growth factor receptor (EGFR), which is a transmembrane protein with intrinsic kinase activity that can initiate downstream signaling pathways.

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