Which metabolites can potentially accumulate when complex I of the electron transport chain is defective?
Q: For the equations below, which molecule is oxidized and which is reduced? H2S + NAD+ --> NADH +…
A: The chemical reaction of losing and accepting electrons is known as a redox reaction. In a redox…
Q: electron transport chain,
A: The ETC stands for Electron transport chain process that occurs in the mitochondria. It helps to…
Q: Which of the following is an electron carrier that shuttles electrons between various protein…
A: The electron transport chain (Figure 1) is the last component of aerobic respiration. Electron…
Q: In the electron transport chain, NADH is oxidized at complex ____, and FADH2 is oxidized at complex…
A: Reduced coenzymes NADH and FADH2 retains most of the free energy produced during the process glucose…
Q: When unlimited energy (glucose = 100 and fat = 100) is available and pyruvate processing is…
A: The electron transport chain is a series of electron transporters embedded in the inner…
Q: During oxidative phosphorylation, the proton motive force that is generated by electron transport is…
A: Ans- During oxidative phosphorylation, the proton motive force that is generated by electron…
Q: In the ETC, FADH2 transfers electrons via Complex II. Select one: True False NADH is derived from…
A: Electrons are transferred from NADH/FADH2 to oxygen, the terminal electron acceptor in aerobic…
Q: As an end result of electron transfer through the transport chain in mitochondria 1. pH in…
A: Electron Transport Chain (ETC) occurs in mitochondria in which the protein complexes transfer the…
Q: Which of the following is TRUE about NAD+? O It donates electrons for use in oxidative…
A: The chemical processes that take place in the body of a living cell are studied as biochemical…
Q: YA) All of the following satisfy the requirements of Complex V oxidative phosphorylation, EXCEPT…
A: The reduced electron carriers, NADH and FADH2 are produced as a byproduct of glycolysis. The…
Q: In the process of electron and H transport in the mitochondrial inner membrane, which of the…
A: Mitochondria are the membrane-bound organelles that produce the energy required to power the various…
Q: Which of the following best describes the number of NAD+ that get reduced in the matrix reactions:…
A: Note: According to the guidelines, we are supposed to answer only 1 question. Please repost other…
Q: How is a gradient of H+ ions formed across the inner mitochondrial membrane? The electron transport…
A: The cells require energy to perform various functions. The energy is provided in the form of ATP.…
Q: What is the main driving force for massive production of ATP molecules in the mitochondria? 1 point…
A: "Since you have asked multiple questions, we will solve the first question for you. If you want any…
Q: Which of the following is the most likely explanation for a situation where the ELECTRON TRANSPORT…
A: The electron transport chain is made up of membrane-embedded proteins and organic compounds that are…
Q: The two electron carriers involved in the redox reactions of cellular respiration are NAD+ and FAD.…
A: Oxidation- reduction reaction is also called as redox reactions. It is a type of chemical reaction…
Q: The above reaction (FADH2 donating its electrons to the electron transport chain) takes place in…
A: Introduction In an electron transport chain, electrons move from one complex to another complex…
Q: Which of the following statements about the electron transport chain is TRUE? O The movement of…
A: Answer is option 4 and 5.
Q: Why does mitochondrial NADH yields more ATPs than cytosolic NADH?
A: NADH is also called a reduced compound. NADH molecules are generated inside the cell through…
Q: Match the stage of cellular respiration to the correct location. options: Mitochondrial matrix…
A: Mitochondria A double membranous organelle that help in production of ATP molecules.
Q: In normal mitochondria, which of the following is true for the rate of NADH consumption (oxidation)?…
A: Mitochondria occupy a significant part of the cytoplasmic extent of eukaryotic cells, and that they…
Q: Diagram the investment and release of Energy and Carbonatoms from Glycolysis through the Citric Acid…
A: The cellular respiration involves the series of glycolysis, Krebs cycle and electron transport chain…
Q: Reagents, such as dinitrophenol, increase the permeability of the mitochondrial inner membrane to…
A: The mitochondrion is a semi autonomous double-membrane-bound organelle found in most eukaryotic…
Q: n eukaryotic cells, most of the enzymes of the electron transport chain are located in the—…
A: Enzymes are defined as the type of protein substances that act as a biological catalyst in the body…
Q: Consider the function of the cofactor FAD. Which of the following makes it unique (different) from…
A: FAD stands for flavin adenine dinucleotide in its oxidised condition. FADH2 is the name given to it…
Q: which of the following woudl decrease the number of atp molecules generated per nadh molecule in the…
A: Electron transport chain in present mitochondria and it consists of various complex and the atp…
Q: true about the electron transport chain (ETC) and oxidative phosphorylation? A. Oxidative…
A: The synthesis of ATP from ADP involving oxidative reactions is known as oxidative phosphorylation.
Q: Which of the following components of the mitochondrial electron transport chain is not integral to…
A: The electron (ETS) transport system is the final metabolic pathway. In this pathway, an electron is…
Q: Which of the enzymes discussed in this chapter are NADHlinked dehydrogenases?
A: NADH linked dehydrogenases are the members of family of enzyme that converts NAD from its reduced…
Q: Which complex of the mitochondrial electron transport chain accepts electrons directly from NADH…
A: The Electron transport chain involves a chain of electron transporters that goes through redox…
Q: Describe the processes that are driven by mitochondrial electron transport.
A: Electron transport is part of cellular respiration.
Q: Which complex of the mitochondrial electron transport chain accepts electrons directly from NADH…
A: All the living organisms require energy to conduct proper functioning. The energy is obtained…
Q: respiratory complexes is involved in the flow of electrons from NADH to O2 except
A: The cellular respiration is a reaction or a process by which the cells of the body breakdown the…
Q: Which of the following statements is NOT true about the electron transport chain (ETC) and oxidative…
A: Electron transport chain (ETC): It is a series of four protein complexes that create an…
Q: Discuss the metabolic roles played in cells by the coenzyme NAD+ and NADP+
A: NAD+ and NADP+ are coenzymes that act as metabolites of ATP. They act as an electron carrier in many…
Q: What thermodynamic force drives the transport of ADP and Pi into the mitochondrial matrix for ATP…
A: The electron transport (ETS) chain is present in the mitochondria, which helps in the formation of…
Q: The image shows the flow of electrons through electron carriers I, II, III, and IV within the…
A: Electron transport chain is the final aspect of cellular respiration that occurs in the…
Q: Which of the following is the major source of electrons that flow through the mitochondrial electron…
A: Cellular respiration refers to a process by which energy is obtained for various life processes…
Q: Which of the following statements about the generation of ATP in the electron transport chain is…
A: Which of the following statements about the generation of ATP in the electron transport chain is…
Q: In the section dealing with “NAD+ in disease” it is mentioned that metabolomics results indicate…
A: Complex I is the first enzyme of the respiratory chain. It oxidizes NADH, which is generated through…
Q: Which of the following electron carriers diffuses within the inner mitochondrial membrane to…
A: Aerobic cellular respiration is a set of three basic metabolic processes that occur in cells to…
Q: The Fo subunit of the ATP synthase is present in the ______ while the F1 subunit is in the ____.…
A: The ATP synthase is described as a mitochondrial enzyme that is localized in the inner membrane.…
Q: Fill in the bold using the table. Because the inner mitochondrial membrane is impermeable to L,…
A: Acetyl-CoA is produced by the breakdown of both carbohydrates and lipids. It then enters the citric…
Q: After radioactive carbon was fed into the citric acid cycle, where might it be found? A. ATP…
A: Radioactive 14C are fed into the citric acid cycle as radioactive isotopes labeled on an acetyl-CoA.…
Q: In the section dealing with “NAD+ in disease” it is mentioned that metabolomics results indicate…
A: NADH-coenzyme Q oxidoreductase, also known as NADH dehydrogenase or complex I, is the first protein…
Q: E A C F В H O2 G Fumarate
A: The electron transport chain is a process in which the NADH and [FADH2] that is produced during…
Q: There are some drugs that can inhibit the activity of ATP synthase. How does this affect the pH of…
A: ATP synthase is an enzyme, which directly generates adenosine triphosphate (ATP) during the…
Q: Which statement is correct in describing the electron transport chain (ETC)? Electron transfer in…
A: All cells require energy (ATP) to carry out various cellular processes, such as active transport,…
Q: All of the following components of the mitochondrial electron transport chain contain several…
A: The mitochondrial respiratory enzyme complexes are embedded in the inner membrane of the…
Q: Provide a simplified schematic presentation (metabolic map) of mitochondrial beta-oxidation. Include…
A: Mitochondrial beta oxidation is an aerobic process. oxidation of acyl CoA derivatives catalysed by…
. In the section dealing with “NAD+ in disease” it is mentioned that metabolomics results
indicate that impaired mitochondrial function contributes to some of the mentioned
diseases. Which metabolites can potentially accumulate when complex I of the
electron transport chain is defective?
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- In the section dealing with “NAD+ in disease” it is mentioned that metabolomics resultsindicate that impaired mitochondrial function contributes to some of the mentioneddiseases. Which metabolites can potentially accumulate when complex I of theelectron transport chain is defective? Use Fig 1 for guidanceFill in the bold using the table. Because the inner mitochondrial membrane is impermeable to L, when there is an excess of mitochondrial L, it converts to M using a TCA condensation reaction, M crosses to the cytosol using a designated transport system. In the cytosol, M reconverts to L and oxaloacetate. Oxaloacetate is subsequently converted to malate with simultaneous production of N, a prerequisite cofactor for the glycolysis pathway. This reaction is then followed by conversion of N to pyruvate which produces O, a prerequisite cofactor for the fatty acid synthesis pathway. L M N O A. ATP pyruvate malate NADPH B. ATP citrate ATP NAD+ C. acetyl CoA pyruvate NAD+ NADH D. acetyl CoA citrate NAD+ NADPH E. glucose pyruvate malate NADP+DCCD (diocyclohexylcarbodiimide) inhibits oxidative phosphorylation when the substrate is mitochondrial NADH. DCCD is a drug that binds to ATP synthase and blocks proton transport through the ion channel. a) Explain what the consequences of DCCD on cellular energy production are. b) Suggest at least one other cellular effect of DCCD and explain this effect.
- Using the answer code on the right, indicate which form of energy production is being described: 1. takes place in the mitochondrial matrix 2. produces H2O as a by-product 3. results in a rich yield of ATP 4. takes place in the cytosol 5. processes acetyl-CoA 6. takes place in the mitochondrial innermembrane cristae 7. converts glucose into two pyruvate molecules 8. uses molecular oxygen 9. accomplished by the electron transport system and ATP synthase (a) glycolysis (b) citric acid cycle (c) oxidative phosphorylationReferring to the figure below, explain why NADH yields more ATP than FADH2 does. Electron-transport and proton pump Oxidative phosphorylation Outer mitochondrial membrane H* -Intermembrane H+ H+ H+ space H* H+ H+ Cytochrome c H+ COQH, CoQ UU COQH2 CoQ JU U Inner mitochondrial membrane Ht e ATPase Complex II Complex II Complex IV Complex e ADP +P - Mitochondrial matrix NADH NAD+ FADH2 FAD АТР H+ -H+ H+ H20a) Make a theoretical calculation of how many ATP molecules can be formed from the breakdown of a molecule of Acetyl- CoA into carbon dioxide and water. The prerequisite is that the entire proton gradient across the mitochondrial inner membrane can be used for ATP production and that the ATP synthase has 6 c-subunits.
- The electron-transport chain consists of a number of multi protein complexes, which work in conjunction to pass electrons from an electron carrier, such as NADH, to O2. What is the role of these complexes in ATP synthesis? It has been demonstrated that respiration supercomplexes contain all the protein components necessary for respiration. Why is this beneficial for ATP synthesis, and what is one way that the existence of super complexes has been demonstrated experimentally? Coenzyme Q (CoQ) is not a protein, but a small, hydrophobic molecule. Why is it important for the functioning of the electron transport chain that CoQ is a hydrophobic molecule?A. what cyclic pathway does this common metabolite enter? B. what are the reduced forms of NAD+ and FAD? What are the entry points for the reduced forms of NAD+ and FAD in the electron transport chain? C. what is the final electron acceptor in the electron transport chain?a) In the common electron transport pathway, electrons move from reduced nicotinamide adenine dinucleotide (NADH) to the terminal electron acceptor found in eukaryotic mitochondria. Discuss the roles of mitochondria as a powerhouse in eukaryotes.
- During the FADH2 electron transport chain, the protons are pumped from the mitochondrial matrix to the intermembrane space through complexes CoQ/III, and IV the protons are pumped from the mitochondrial matrix to the intermembrane space through complexes I, CoQ/III, and IV the protons are pumped from the mitochondrial matrix to the intermembrane space through complexes I, CoQ/II, and IV the protons are pumped from the mitochondrial matrix to the outer mitochondrial membrane through complexes I, III, and IVb) Place a 'Yes' or a 'No' in the appropriate boxes that correspond to each listed feature of cellular respiration. You may need to state 'Yes' or 'No' in more than one box in a particular row in some cases. Cellular Respiration Feature Involved in aerobic respiration Occurs in the mitochondrial matrix Pyruvate molecules are produced Acetyl COA combines with a 4 carbon molecule Electrons are passed between protein carriers ATP is produced NAD+ gains hydrogen FADH₂ loses hydrogen Glycolysis Yes / No Krebs Cycle Yes / No Electron Transport chain Yes / Nob) Place a 'Yes' or a 'No' in the appropriate boxes that correspond to each listed feature of cellular respiration. You may need to state 'Yes' or 'No' in more than one box in a particular row in some cases. Cellular Respiration Feature Involved in aerobic respiration Occurs in the mitochondrial matrix Pyruvate molecules are produced Acetyl CoA combines with a 4 carbon molecule Electrons are passed between protein carriers ATP is produced NAD* gains hydrogen FADH₂ loses hydrogen Glycolysis Yes / No Krebs Cycle Yes / No Electron Transport chain Yes/No 90+