Which component of cell division machinery is frequently targeted by anti-cancer drugs? Can you explain the common side-effects of chemotherapy (e.g. hair loss, mucositis) based on this information?

Q: Can we treat cancer by restoring tumor suppressor function such as mutated p53 or pRb?  If so, how…

A: The process by which a cell gives rise to two identical daughter cells is referred to as cell…

Q: Briefly summarize the conventional wisdom (DNA mutation theory) of the cause of cancer. Discuss the…

A: It  proposes that successive DNA mutations in a single cell cause cancer (monoclonality). This…

Q: Personalized cancer treatments involve identifying specific pathways in an individual tumor and…

A: Introduction Cancer is defined as a condition which is characterised by uncontrolled mitosis. In…

Q: The best strategy for treating a specific type of human tumor can depend on identifying the type of…

A: Cancer is a fatal disease that has both physical and mental consequences for a person. Cancer can…

Q: Chemotherapeutic agents can promote apoptosis in cancer cells by these mechanisms except; Group of…

A: Chemotherapy is a basic component of cancer treatment, aimed at eliminating cancerous cells by…

Q: How can a defect in p53 gene contribute to cancer development?

A: Cancer is an abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some…

Q: Describe the general process of cell signalling pathways: what events take place for a signal to…

A: * mainly there are Three Stages of Cell Signaling . The first one is reception and here the signal…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Induced pluripotent stem cells (iPS) is a type of stem cell(pluripotent) in nature that is derived…

Q: Explain how p53 functions as a tumor suppressor gene. How can mutations in p53 lead to cancer, and…

A: Normal cell has low level of p53 protein. When DNA damage or other stress signals may trigger p53…

Q: Why is it harder to develop a drug that targets a tumor suppressor gene compared to an oncogene…

A: Uncontrolled cell division in the cells may result into the tumor formation. Sometimes the cells may…

Q: Suppose there is a new drug targeting a type of cancer and the clinical trials are to be done with…

A: Human Testing Phases for Investigational DrugsIf the FDA approves the investigational drug, it will…

Q: Cancer cells generally have missense mutations in p53 gene, resulting in truncated p53 normally…

A: A normal cell is converted into a cancer cell when the there is deactivation of the tumor suppressor…

Q: hallmarks of tumor cells

A: Introduction:-The hallmarks constitutes an organizing principle for rationalising the complexities…

Q: What enzyme is upregulated in cancer that overcomes cell senescence?

A: Various type of tumor suppressor genes and oncogenes regulate senescence in normal cell.…

Q: Download and read the attached review article…

A: Some cancer patients would only need one operation. Many patients, on the other hand, undergo a…

Q: What are the normal functions of the BRCA1 tumor suppressor gene?

A: The BRCA1 gene codes for the protein that causes breast cancer type 1. BRCA1 is a human tumour…

Q: Why are deaths from infection in cancer patients so common?

A: Cancer is a condition in which the cells undergoes continuous cycle without stopping and doesn’t…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Genetic transformation happens when the genetic composition of an organism is transformed by the…

Q: Heterotypic interactions of tumor cells have been a fertile area for potential therapeutic…

A: Cancer is a major disorder and it causes development of abnormal cells & they divide…

Q: Discuss the complete cell cycle in a human cell, mitosis and meiosis, and the regulatory components…

A: There are two types of cell division.They are Mitosis and Meiosis. Most of the times,the type of…

Q: Why do mutations in DNA repair genes increase the likelihood of developing cancer?

A: Deoxyribonucleic acid (DNA) is a hereditary molecule that transfers genetic information from one…

Q: The current way to gauge the effectiveness of chemotherapy is to track the size of the tumor. If the…

A: Introduction : The use of  different combination of drugs in the treatment of cancer is referred to…

Q: The p53 gene encodes a tumor-suppressor protein, p53, which acts as a transcription factor for…

A: Answer. Genes for which a gain of function mutation drives a cell towards cancer are called proto…

Q: Describe in detail the relevance of apoptosis to cancer therapy

A: Apoptosis or programmed cell death  It is a highly regulated process that allows a cell to self…

Q: How interfered regulatory machinery results in production of tumor?

A: Eukaryotes have well-organized nucleus. prokaryotes are devoid of nuclear arrangements. genome…

Q: Out of these 8 hallmarks ( sustaining proliferative signaling, evading growth suppressors, resisting…

A: The cells multiply by cell division. It is a controlled process for the growth and development of…

Q: Explain the mechanism of Warburg effect and how it benefits cancer cells

A: The metabolic process of breakdown of glucose under anaerobic conditions that is in the absence of…

Q: Explain how mutations in oncogenes and in tumor suppressorgenes cause cancer.

A: Cancer is a group of diseases that involves abnormal growth of the cell. These cells have the…

Q: Explain the role of p53 protein in protecting normal cells against cancer. With respect to this…

A: The cell is the primary unit of all living entities. The normal cell undergoes some necessary…

Q: In your own words, explain how cancer cells differ from normal cells in regard to the following:…

A: Cancer is a very complex disease that causes a cell to divide uncontrollable. Different causes are…

Q: Explain why some researchers believe science should focus its attention on the inflammation…

A: The uncontrolled growth of cells leads to cancer progression.

Q: What is a method some tumors use to evade restriction of their growth by secreting substances that…

A: Cells are the part of human body which grows and divide to make new cells. They are the basic…

Q: Despite all that we know about cancer today, some types of cancers are still increasing in…

A: Cancer is the title given to a collection of related infections. In all sorts of cancer, a few of…

Q: How can a mutation in a tumor-suppressor gene contribute to the development of cancer?

A: Tumor-suppressor genes are like any other normal genes whose functions include slowing down cell…

Q: Cancer is caused by many different types of gene mutations. Some mutations are in proto-oncogenes,…

A: Cells split into new cells so that the body uses them and cancer starts with this wonderful…

Q: Explain what is fundamental aberrations in all cancer cells ?

A: Answer: Introduction: The features of chromosomal aberrations in cancers, has studied in the 15,000…

Q: Describe the differences between point mutations, chromosomal translocations, and gene amplification…

A: Cancer is a disease that is associated with the uncontrolled division of cells and invasion of…

Q: A research study indicated that an agent in cigarette smoke caused the silencing of a tumor…

A: The TP53 gene provides instructions for making a protein called tumor protein p53 (p53). This…

Q: What is the difference in an oncogene and tumor suppressor gene and how can each potentially lead to…

A: Cancer is group of diseases which are characterized by abnormal and unstoppable growth of cell and…

Q: What is/are the role/s of molecular techniques in understanding cancer? Cite some references from…

A: In cancer, cells grow abnormally. Cancer is not one disease. It is a group of diseases. The…