Use the image below to answer the following questions.   Label the genotypes for ALL the family members in the pedigree above. Remember to use XX and XY when labeling. What does it mean to be a carrier? Why does Alexis have hemophilia? Is hemophilia a sex-linked disease? Wha

You are trying to find a blood donor to help treat some of your patients. The C-yonce and Kay-Z have 3 children with blood types A , B, and O. The youngest with blood type O needs a transfusion and you're trying to figure out if either of the parents are a match so you test the parent genotypes. Note: Alleles for each blood type are expressed as follows: blood type A= I^A blood type B= I^B blood type O= i Hint: Remember that 2 alleles contribute to a persons blood type. Pay attention to dominant and recessive relationships among the alleles.     1-C-yonce is type B. What must her genotype be? 2-What must Kay-Z’s genotype be? 3-Which parent can give blood to their child ? 4-After running lab tests, it was discovered that the children's blood types were reported incorrectly.(This does not affect the genotypes entered for C-yonce and Kay-Z in the previous questions.) Their youngest actually has blood type AB, and still needs a blood transfusion.  Which parent can donate blood to the child…

Hemophilia is due to a sex-linked gene. It is recessive and found on the X chromosome. A woman who is a carrier for hemophilia marries a normal man. What will be the possible phenotypes of their children? (use the letter “H”)

Alice has type A blood and her husband Mark has type B blood. Their first child, Amanda, has type O blood.  Their second child, Alex, has type AB blood. What is Mark's genotype?

The pedigree chart provided below traces the occurrence of a disease through the generations of a family. Determine what type of inheritance pattern this disease has.

Hemophilia, disease in which the blood lacks a clotting factor, is caused by an X linked recessive gene. Joe doe not have hemophilia and Lucille is heterozygous for the condition.  What is the chance that their MALE child will have hemophilia? (Note: you are calculating the probability for their MALE children only, in other words if they have 1 male child, what is the probability that he will be born with the disease?)     0%     1/4 or 25%     2/4 or 50%     3/4 or 75%     4/4 or 100%

A female with genotype IBi has a child that has blood type O (genotype ii). Which of the following genotypes could the child's father have? Select all correct answers.   ii IAIB IAi IBIB

Adenike and her partner, Debare, are expecting their first child. Adenike is healthy as are her two sisters but her brother has PKU, a recessive disorder of the PAH gene. Genotypically he must be pah-/pah-. Neither of Adenike's parents has PKU but both of her grandmothers did. Debare is a carrier of Sickle Cell trait, which means he has one allele for wildtype hemoglobin (HbA) and one allele for Sickle Cell (HbS), making him HgA/HbS. More importantly, he has two alleles for Marfan Syndrome, a pleiotropic dominant disorder that can affect up to 30 different traits (M+/M+). No one in Debare's family has ever had PKU and no one in Adenike’s family has ever had Sickle Cell or Marfan Syndrome. They consult a genetics counselor over concern of the health of their baby. The genetics counselor collects the medical histories of three generations; their grandparents, their parents, and them. In her calculations, she produces a phenotypic key that indicates M = Marfan, Hb = sickle cell, and pah-…

Cystic fibrosis is a genetic disease that causes an abnormal production of mucus which in turn can cause damage and infection to the lungs and other organs. In the following pedigree, black indicates all those persons afflicted with cystic fibrosis (square symbols are males, circles are females). There's a healthy couple and they have two children. One is a 23-year-old daughter with cystic fibrosis who is married to a 24-year-old male who is healthy. The other child is a 15-year-old son who is healthy After studying the pedigree, write a logical hypothesis suggesting the cause of cystic fibrosis in terms of dominant or recessive alleles.  On the basis of your hypothesis, write an appropriate genotype for both of the  parents.  Using a Punnett square, what is the probability of the parents having a child with cystic fibrosis?  If the daughter's husband is a carrier of cystic fibrosis, what is the probability that they have a child with cystic fibrosis? Show your Punnett square.

The pedigree below shows a family affected by a disease. Assume that the individuals marked with an asterisk (*) do not carry any allele associated with the affected phenotype, no other mutation spontaneously occurred, and complete penetrance. Answer the following questions below. Use the notation XR for the allele associated with the dominant phenotype and Xr for the allele associated with the recessive phenotype. Q1) Give the genotypes for as many individuals in the pedigree as possible.