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Different types of signaling between cells
Briefly describe the 6 different signal paths
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- Create a diagram which illustrates the typical signalling mechanism of action of nuclear receptors and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways thgt are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. for a novel pathway. Superfamily Give the superfamily to which the receptor belongs Accession Give the Uniprot accession number Name Give the molecule name Species Give the species Ligand What is the ligand, or class of ligands which bind to this receptor? Key physiological What are the physiological processes involved? Is this autocrine, paracrine or endocrine or some combination of them? What is the pathology of the receptor? process involved Mechanism of What are the downstream actions of the receptor? Which molecules does…How do signaling proteins form specific complexes? Provide examples.Pane Create a diagram which illustrates the typical signalling mechanism of action of g protein coupled and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. for a novel pathway. Superfamily Give the superfamily to which the receptor belongs Accession Give the Uniprot accession number Name Give the molecule name Species Give the species Ligand What is the ligand, or class of ligands which bind to this receptor? Key What are the physiological processes involved? Is this autocrine, physiological paracrine or endocrine or some combination of them? What is the pathology of the receptor? process involved What are the downstream actions of the receptor? Which molecules does it…
- Create a diagram which illustrates the typical signaling mechanism of action of g protein coupled land possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. for a novel pathway.1a) Create a diagram which illustrates the typical signaling mechanism of action G protein-coupled receptors and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can for a novel pathway.How would signaling between two cells e affected by the following mutation: occludes (NA) (obtains new function that induces large gaps)
- Illustrate a complete cell signaling cascade from signal to response. Each protein in the pathways must be shown. You can choose either a GPCR or an RTK mediated pathway.Why do we need to identify and determine the function of every single molecule involved in cell signalling? Provide one concrete example of an application of an elucidated cascade of events in cell signalling. (The answer should be no less than 300 words)27) Fill in the blanks Cells adjacent to one another frequently communicate through Other forms of cell-cell communication through In extracellular signaling ligand-receptor interaction induce; 28) Cell-to-cell communication by extracellular signaling usually involves six steps , sort the below given steps according to happening order; Removal of the signal, which usually terminates the cellular response – degradation of ligand- A change in cellular metabolism, function, or development CELLULAR RESPONSE triggered by the receptor-ligand complex – specific to the ligand-receptor complex Release of the signaling molecule by the signaling cell Transport of the signal to the target cell Synthesis of the signaling molecule by the signaling cell Detection of the signal by a specific receptor protein (receptor-ligand specificity 29) Polyethylene can be obtained in two different forms. High-density polyethylene (0.94 g/cm3) is a linear polymer. Low-density polyethylene (0.92 g/cm3) is a…
- Explain how an indirect neurotransmitter receptor mechanism (like A-G linked receptor) conduct cell signaling?Much of what we know about cell signalling comes from biochemical studies of proteins isolated in test tubes. What is the precise quantitative behaviour of intracellular signalling networks in an intact cell where countless other signals and cellular components can influence the specificity and intensity of signalling?Cite evidence supporting a long evolutionary history for cell signaling molecules.