This type of ion channel allows K+ ions to flow into or out of a cell down its concentration gradient. voltage-gated ligand-gated Leak Na+/K+ ATP pump
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- Choose high or low When the ion binding sites pumps are open to the inside of the cell the pump has a high/low affinity to potassium and a high/low affinity for sodium. When the ion binding sites are open on the outside the pump has a high/low affinity to potassium and a high/low affinity to sodiumA cell has a membrane potential of -100 mV (more negative inside than outside) and has 1,000 times more calcium ions outside the cell than inside. Which best describes a mechanism by which Ca2+ enters this cell? facilitated diffusion of Ca2+ into the cell down its electrochemical gradient movement of Ca2+ into the cell through an ion channel down its concentration gradient passive diffusion of Ca2+ into the cell down its electrochemical gradient cotransport of Ca2+ into the cell with Cl- movement of Ca2+ into the cell through a carrier protein down its electrical gradient I know that the answer is 1 but please explain why. Thank you.Ligand binding of a (????) causes conformational changes in the receptor that free the associated G-protein to interact with other membrane proteins Voltage gated ion channel GPCR Ligand gated ion channel Ligandase pore
- The resting membrane potential is established by? The Na+/K+-ATPase pumping Na+ into the cell and K+ out of the cell The Na+/K+-ATPase pumping K+ into the cell and Na+ out of the cell A larger diffusion of K+ out of the cell compared to diffusion of Na+ into the cell A larger diffusion of K+ into the cell compared to diffusion of Na+ out of the cell a) and d) b) and c)How is the cell membrane like a battery? Membrane potential (think of the properties of a battery) Resting membrane potential Na+ and K+ ions -> -70 mV Na+/K+ pump Stored energy for workThe rapid upstroke of a SA nodal cell action potential is due to the opening of voltage-gated Na+ channels. answer should clearly state whether or not the statement is correct and then concisely explain why. the answer should be 3-5 sentences and address all of the points in the statement. Here is an example: Both transmembrane carrier proteins and transmembrane channel proteins can mediate active transport of a hydrophilic solute through a cell plasma membrane. This statement is incorrect. Movement of a solute through a channel protein is always passive, whereas carrier-mediated transmembrane transport can be either passive or active. A transmembrane channel protein creates a pore through the membrane allowing for simple diffusion of a hydrophilic solute down a concentration gradient through the membrane. In contrast, transmembrane carrier protein interacts with and ‘escorts’ a hydrophilic solute through the membrane and is capable of transporting a solute against a concentration…
- Let’s say that the intracellular tonicity is 300 mosm. Checkmark the correct response to what would happen to the cell when it is placed in the following solutions prepared from sucrose (impermeable), NaCl (impermeable), and urea (permeable). Solution Nothing Swell Shrink 100 mM sucrose 200 mM NaCl 300 mM urea 300 mM NaCl 100 mM sucrose + 100 mM NaCl 100 mM ureaExplain the mechanism of action of the Na+/K+ pump. If these pumps became non-functional due to a genetic mutation, what do you think would be the expected effect on the electrochemical membrane potential of the cell? Explain your reasoning.Which of the following can be correctly applied to gap junctions? Select all that apply Allows small molecules and ions to travel between cells They are membrane channels that allow communication between neighboring cells O Prevents cells from separating from one another O They behave as gated ion channels
- Some cytoplasmic kinases, enzymes that phosphorylate substrates at the expense of ATP, bind to voltage-dependent anion channels. What might the advantage of this binding be?The membrane of most cells, including neurons, contains passive, open, K' leak channels. Given the normal K' concentrations and the resultant concentration gradient, which direction would K' be expected to move (diffuse) through these leak channels? Select one: 1/into the cell 2/out of the cellAn analog of cGMP, 8-Br-cGMP, will permeate cellular membranes, is only slowly degraded by a rod cell’s PDE activity, and is as effective as cGMP in opening the gated channel in the cell’s outer segment. If you suspended rod cells in a buffer containing a relatively high [8-Br-cGMP], then illuminatedthe cells while measuring their membrane potential, what would you observe?
