The insulin that does not have a peak of action is:A. Glulisin (Apidra)B. Glargine (Lantus)C. Isophane (Protaphane)D. Biphasic Insulin N 70/30E. Aspart (Novolog)
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The insulin that does not have a peak of action is:
A. Glulisin (Apidra)
B. Glargine (Lantus)
C. Isophane (Protaphane)
D. Biphasic Insulin N 70/30
E. Aspart (Novolog)
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Solved in 2 steps
- Which of the following classes of compounds stimulates the release of insulin from pancreatic β-cells? a. Thiourylenes b. Biguanides c. Progestins d. Sulfonylureas e. α-Glucosides inhibitorsAll of the following medications are types of insulin, except:A. Aspart (Novolog)B. Glargine (Lantus)C. Lispro (Humalog)D. Glulisin (Apidra)E. Exenatide (Byetta)Insulin formulation that has a very fast onset of action is:A. Glargine (Lantus)B. Soluble human (Humodar)C. Lispro (Humalog)D. Human Isophane (Фармасулін НNP)E. Detemir (Levemir)
- Insulin preparations can have the following durations of action:A. Fast and longB. Fast, medium and longC. Polar, non-polar, neutralD. Very fast, fast, medium and longE. Subpolar, polar, non-polarInsulin is obligatory in the following states, except:A. Light course of type 2 diabetes mellitusB. Pregnancy in patients with type 2 diabetes mellitus C. Lactation in patients with type 2 diabetes mellitusD. Ketoacidosis in patients with type 2 diabetes mellitusE. Surgery in patients with type 2 diabetes mellitusAll of the following increase insulin secretion/production EXCEPT: Select one or more: a. Increased intracellular Ca²+ levels O b. Acetylcholine O C. Ghrelin O d. High carbohydrate meal e. Incretins O f. Sometostatin
- Insulin therapy has all of the following effects, except:A. Increases concentration of free fatty acids in blood plasma B. Stimulates glucose uptake by tissuesC. Inhibits lipolysisD. Activates protein synthesisDefine the following terms:a. second messengerb. desensitizationc. target celld. insulin resistancee. adenylate cyclaseInsulin should be prescribed under all of the following circumstances, except:A. Status post pancreatectomyB. Type 2 diabetes with diabetic foot syndrome C. Type 1 diabetesD. Gestational diabetesE. Type 2 diabetes
- Which of the following medications does not have hypoglycemic effects (does not augment insulin activity)?A. Glicised (Glicinum)B. SalicylatesC. SulfanilamideD. EthanolE. FluoxetineIdentify the partial sequence of events that occurs after the insulin binds to its receptor. 1. Phosphorylation of insulin receptor substrate (IRS-1) 2. Activation of the receptor tyrosine kinase activity 3. Activation of phosphodiesterase 4. Activation of phospholipase C 5. Phosphorylation of phosphatidylinositol 6. Activation of phosphatidylinositol-3 -kinase (P1-3 kinase) 7. Binding of Grb 2 8. Activation of a phosphatase 9. Dephosphorylation of pyruvate kinase 10. phosphorylation of pyruvate kinase 2-7-1-4-3-9 1-7-3-5-6-8 2-1-6-5-8-9 2-7-1-6-5-8-9 2-7-4-6-1-8-10Which of the following medications does not have hyperglycemic effects (does not decrease insulin actions)?A. Calcium channel blockersB. Beta 2 agonistsC. PentoxifyllineD. H2 histamine receptor blockersE. Isoniazid