The family below has the autosomal dominant trait of dimples.  In this family, I-1 and I-2 are known to be heterozygous.  It is not known whether any other individuals in this family are heterozygotes.  If Narayan and Pritya have a child, what is the chance it will NOT have dimples?

Sickle cell anemia is a recessive trait in humans. In a cross between a father who has sickle cell anemia and a mother who is heterozygous for the sickle cell allele, what is the probability that both of their first two children will be affected? A) none B) 1/16 C) 1/8 D) ¼ E) ½

In humans, albinism (lack of skin pigment) is an autosomal recessive trait. The first child of two normally pigmented parents is an albino. Which of the following is true about this family? SELECT ALL THAT ARE CORRECT. A) Their first child (described above) has a homozygous recessive genotype B) The next child born to this couple has a 25% chance of being albino. C) If the next child born to this couple is male, he has a greater chance of being albino. D) The parents are both heterozygous for albinism. E) The probability of their second child being albino is 0% F) If the second and third child born to this couple are albino, the fourth child has 100% chance of also being albino.

Stacey and Rishi are expecting fraternal twins, a boy and a girl. Stacey and Rishi have normal vision, but both of their fathers are colour vision deficient (CVD, a X-linked recessive trait). a) Draw a pedigree for their family b) Complete a Punnett square to show the cross between Stacey and Rishi. c) What is the probability that the baby will be a girl with CVD? d) What is the probability that the baby will be a boy with normal vision?

The three genes X, Y, and Z are linked on an autosomal chromosome in humans (X to Y is 15 cM, and Y to Z is 18 cM). If an individual that is heterozygous at all three loci (XYZ/xyz) has children with an individual that is homozygous recessive at all three loci (xyz/xyz), what is the probability that they will have a child that is phenotypically identical to either parent (X-Y-Z- or xxyyzz)? Assume there is no genetic interference to double crossover events at this site.

A heterozygous inidividual with blood type A marries a heterozygous individual with blood type B. What blood types could their offspring exhibit? A)all of these are possibleB)ABC)AD)OE)B

Which of the 6 modes is this pedigree and why? 1) Autosomal Dominant 2) Autosomal Recessive 3) X-linked Recessive 4) X - linked Dominant 5) Y-Linked 6) mt-Linked

An unaffected woman for a human disorder marries and unaffected man and they have children. This results in 3 affected sons, and one unaffected daughter, which ends up having children later on with an unaffected man and has 2 affected sons. A) Draw a simple pedigree diagram for this family, including a legend. B) What is the likely mode of inheritance of this trait: Please explain C) Provide the genotypes of the original mother and the daughter. Use a capital letter for the dominant allele and lowercase letter for the recessive allele. D) If one of the affected sons from the original marriage marries a 2nd cousin that is a carrier of this trait and has children, what is the probability that they will have 3 affected sons?

Now assume that the pedigree shown in question 1 shows the inheritance of a rare genetic disease. a) The disease is most likely autosomal dominant b) The disease is most likely autosomal recessive c) The disease is equally likely to be either autosomal dominant or autosomal recessive, but cannot be x-linked d) Cannot be determined from the information given

The following pedigree illustrates the inheritance of ringed hair, a condition in which each hair is differentiated into light and dark zones. What mode or modes of inheritance are possible for the ringed-hair trait in this family? 2 II 2 3 4 5 6 II 2 3 4 5 IV