
MATLAB: An Introduction with Applications
6th Edition
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Example 11.1 Please solve using R. Obstetricians sometimes order tests for es-
triol levels from 24-hour urine specimens taken from preg-
nant women who are near term, because level of estriol has
been found to be related to infant birthweight. The test
can provide indirect evidence of an abnormally small fetus.
The relationship between estriol level and birthweight can
be quantified by fitting a regression line that relates the
two variables. Data is given in Table 11.1 on page 459.

Transcribed Image Text:the
ed.
11.2
General Concepts
459
TABLE 11.1
Sample data from the Greene-Touchstone study relating birthweight
and estriol level in pregnant women near term
Estriol
Birthweight
(mg/24 hr)
(g/100)
Estriol
(mg/24 hr)
Birthweight
(g/100)
X;
Y₁
Xi
Yi
2
12
7
25
17
17
32
9
25
18
25
32
3
9
25
19
27
34
4
12
27
20
15
34
5
14
27
21
15
34
6
16
27
22
15
35
7
16
24
23
16
35
8
14
30
24
19
34
9
16
30
25
18
35
10
16
31
26
17
36
11
17
30
27
18
37
12
19
31
28
20
38
13
21
30
29
22
40
14
24
28
30
25
39
15
15
32
31
24
43
16
16
32
EQUATION 11.2
DEFINITION 11.2
EXAMPLE 11.4
EXAMPLE 11.5
Source: Based on the American Journal of Obstetrics and Gynecology, 85(1), 1-9, 1963.
Let's assume e follows a normal distribution, with mean 0 and variance o². The full
linear-regression model then takes the following form:
y = a+ẞx+e
where e is normally distributed with mean 0 and variance σ².
For any linear-regression equation of the form y=a+ẞx+e, y is called the depen-
dent variable and x is called the independent variable because we are trying to
predict y as a function of x.
Obstetrics Birthweight is the dependent variable and estriol is the independent
variable for the problem posed in Example 11.3 because estriol levels are being used
to try to predict birthweight.
One interpretation of the regression line is that for a woman with estriol level x,
the corresponding birthweight will be normally distributed with mean a + ẞx and
variance o². If σ2 were 0, then every point would fall exactly on the regression line,
whereas the larger o² is, the more scatter occurs about the regression line. This rela-
tionship is illustrated in Figure 11.2.
How can ẞ be interpreted? If ẞ is greater than 0, then as x increases, the expected
value of y = a + ẞx will increase.
Obstetrics This situation appears to be the case in Figure 11.3a for birthweight (y) and
estriol (x) because as estriol increases, the average birthweight correspondingly increases.
If ẞ is less than 0, then as x increases, the expected value of y will decrease.
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