The drugs you evaluated in your disc susceptibility tests have different potencies (see table C1; disc content). Which ONE of the following options, based on the laboratory data alone, is the most approapriate in the treatment of a patient with a UTI ?Select one:A.All the above drugs (A, B, C and D) could be consideredB.Trimethoprim (zone size 30 mm) C.Ampicillin (zone size 25 mm)D.Amoxicillin (zone size 15 mm)E.Cephalexin (zone size 25 mm) Table C1: Interpretative values for disc susceptibility evaluation of coliforms, E. coli and Proteus mirabilis to antimicrobialscommonly used to treat urinary tract infectionsAntibioticAmoxicillinAmpicillinCephalexinCiprofloxacinCo-amoxiclaveFosfomycing.hMecillinamNalidixic acidNitrofurantoinNorfloxacinTrimethoprimMIC BP (mg/L)R>3232324321288163242S≤3232324321288163242Disc content(µg)252530120/10200/50103020022.5R<1111-1911171516ColiformsI--Interpretation of zone diameters (mm)E. coli2_12 12-20 12--18-16 17SzR≤1111151911191317191516Sz R≤12 12 16 20 12 20 14 18 20 16 1711111119113314 1318 171516Pr. mirabilis|212 12 12 20 12 34 14 18-16 17Sz

Answered: The drugs you evaluated in your disc…

Human Anatomy & Physiology (11th Edition)

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ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question

The drugs you evaluated in your disc susceptibility tests have different potencies (see table C1; disc content). Which ONE of the following options, based on the laboratory data alone, is the most approapriate in the treatment of a patient with a UTI ?

Select one:

All the above drugs (A, B, C and D) could be considered

Trimethoprim (zone size 30 mm)

Ampicillin (zone size 25 mm)

Amoxicillin (zone size 15 mm)

Cephalexin (zone size 25 mm)

Table C1: Interpretative values for disc susceptibility evaluation of coliforms, E. coli and Proteus mirabilis to antimicrobials
commonly used to treat urinary tract infections
Antibiotic
Amoxicillin
Ampicillin
Cephalexin
Ciprofloxacin
Co-amoxiclave
Fosfomycing.h
Mecillinam
Nalidixic acid
Nitrofurantoin
Norfloxacin
Trimethoprim
MIC BP (mg/L)
R>
32
32
32
4
32
128
8
16
32
4
2
S≤
32
32
32
4
32
128
8
16
32
4
2
Disc content
(µg)
25
25
30
1
20/10
200/50
10
30
200
2
2.5
R<
11
11
-
19
11
17
15
16
Coliforms
I
-
-
Interpretation of zone diameters (mm)
E. coli
2_12 12-20 12--18-16 17
Sz
R≤
11
11
15
19
11
19
13
17
19
15
16
Sz R≤
12 12 16 20 12 20 14 18 20 16 17
11
11
11
19
11
33
14 13
18 17
15
16
Pr. mirabilis
|
212 12 12 20 12 34 14 18-16 17
Sz

Expert Solution

Step 1

Urinary tract infection is a type of infection which mainly affects ureters, kidney, bladder and urethra. Mostly urethra and bladder is affected. Mainly seen in womans then man usually between 20 to 50 years of age. In woman, cyctitics or pyelonephritis mainly involved while in man urethritis and prostatitis. Most bacteria involved are Escherichia coli ( 75 to 95% ), Klebsiella, Proteus mirabillis and Pseudomona aeruginosa. Gram positive include Staphyloccus saprophyticus, Enterococcus fecalis, Streptococcus agalatiae.