+ [Template] SAS4

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter3: Biological Macromolecules
Section: Chapter Questions
Problem 20RQ: How does the double helix structure of DNA support its role in encoding the genome? The...
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[Template] SAS4
6
PART 5: Mutations Background Information
Mutations are changes in the DNA of an organism. These mutations can be harmful, helpful or neutral
(not having any impact on the organism at all.) There are three types of mutations-insertion, deletion and
substitution.
Substitution mutations occur when a single base pair is substituted for the correct base. For example, if a
section of DNA is ATTCG, the mutated strand could be ATTGG.
Insertion mutations occur when one or more base pairs is added (inserted) to a DNA sequence. For
example, if a section of DNA is ATTCG, the mutated strand could be ATATCG.
Deletion mutations occur when one or more base pairs are omitted from a DNA sequence. For example,
if a section of DNA is ATTCG, the mutated strand could be ATCG.
Mutations can happen for several reasons.
A. DNA fails to copy accurately. Most of the mutations that we think of are "naturally-occurring." For
example, when a cell divides, it makes a copy of its DNA – and sometimes the copy is not quite
perfect. That small difference from the original DNA sequence is a mutation.
B. Mutations can be caused by environmental factors such as Ultraviolet Radiation (UV), X-rays and
smoking tobacco. Examples of diseases caused by environmental factors resulting in mutations
would be skin and lung cancer.
C. A mutation can be inherited if it exists in a sperm or egg cell. Examples of common inherited
mutations cause Cystic Fibrosis, Huntington's and Hemophilia.
19. Summarize what you learned from the reading to answer the question- What causes mutations?
II
Transcribed Image Text:12:18 # א [Template] SAS4 6 PART 5: Mutations Background Information Mutations are changes in the DNA of an organism. These mutations can be harmful, helpful or neutral (not having any impact on the organism at all.) There are three types of mutations-insertion, deletion and substitution. Substitution mutations occur when a single base pair is substituted for the correct base. For example, if a section of DNA is ATTCG, the mutated strand could be ATTGG. Insertion mutations occur when one or more base pairs is added (inserted) to a DNA sequence. For example, if a section of DNA is ATTCG, the mutated strand could be ATATCG. Deletion mutations occur when one or more base pairs are omitted from a DNA sequence. For example, if a section of DNA is ATTCG, the mutated strand could be ATCG. Mutations can happen for several reasons. A. DNA fails to copy accurately. Most of the mutations that we think of are "naturally-occurring." For example, when a cell divides, it makes a copy of its DNA – and sometimes the copy is not quite perfect. That small difference from the original DNA sequence is a mutation. B. Mutations can be caused by environmental factors such as Ultraviolet Radiation (UV), X-rays and smoking tobacco. Examples of diseases caused by environmental factors resulting in mutations would be skin and lung cancer. C. A mutation can be inherited if it exists in a sperm or egg cell. Examples of common inherited mutations cause Cystic Fibrosis, Huntington's and Hemophilia. 19. Summarize what you learned from the reading to answer the question- What causes mutations? II
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