Tay-Sachs disease most likely demonstrates what type of inheritance? Pedigree information regarding the incidence of Tay-Sachs within a family is depicted above. The row below that indicates the genotypes of individuals II-1, II-2, and III-1 is
A defective gene on chromosome 15 causes Tay-Sachs disease. It is a central nervous system neurodegenerative disease that most often affects infants, though older children and adults can have late-onset forms of the disease. The defective gene prevents the body from making a protein called hexosaminidase A. Without, hexosaminidase A, chemicals called gangliosides build up in the nerve cells of the brain, destroying brain cells.
A couple has one daughter with Tay-Sachs disease and three other unaffected children. Neither the mother, nor father, nor any of the biological grandparents of the affected daughter have had the disease. Tay-Sachs disease most likely demonstrates what type of inheritance?
Pedigree information regarding the incidence of Tay-Sachs within a family is depicted above. The row below that indicates the genotypes of individuals II-1, II-2, and III-1 is
| II-1 | II-2 | III-1 |
|---|---|---|
| Aa | Aa | aa |
| II-1 | II-2 | III-1 |
|---|---|---|
| XAY | XAXa | XAXa |
| II-1 | II-2 | III-1 |
|---|---|---|
| XAY | XAXA | XaXa |
| II-1 | II-2 | III-1 |
|---|---|---|
| AA | aa | Aa |
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