Lesch-Nyhan syndrome is caused by a X-linked recessive mutations. Accordingly, Lesch-Nyhan syndrome _______. Group of answer choices - occurs more frequently in males than in females - occurs with equal frequency in males and females, but is more severe in males - occurs with equal frequency in males and females, but is more severe in females - occurs with equal frequency in males and females - occurs more frequently in females than in males

Lesch-Nyhan syndrome is caused by a X-linked recessive mutations. Accordingly, Lesch-Nyhan syndrome _______. Group of answer choices - occurs more frequently in males than in females - occurs with equal frequency in males and females, but is more severe in males - occurs with equal frequency in males and females, but is more severe in females - occurs with equal frequency in males and females - occurs more frequently in females than in males

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter4: Pedigree Analysis In Human Genetics

Section: Chapter Questions

Problem 17QP: Analysis of X-Linked Dominant and Recessive Traits A young boy is color-blind. His one brother and...

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Duchenne muscular dystrophy is an X-linked, recessive disorder in which muscles waste away early in life, resulting in death in the teens or twenties. A man and woman in their late thirties have five children—three boys (ages 1, 3, and 10 years) and two girls (ages 5 and 7 years). The oldest, boy shows symptoms of the disease. What are the probabilities that their other children will develop the disease? Give only typing answer with explanation and conclusion
Analysis of X-Linked Dominant and Recessive Traits A young boy is color-blind. His one brother and five sisters are not. The boy has three maternal uncles and four maternal aunts. None of his uncles children or grandchildren is color-blind. One of the maternal aunts married a color-blind man, and half of her children, both male and female, are color-blind. The other aunts married men who have normal color vision. All their daughters have normal vision, but half of their sons are color-blind. a. Which of the boys four grandparents transmitted the gene for color blindness? b. Are any of the boys aunts or uncles color-blind? c. Is either of the boys parents color-blind?
Red-green color blindness in humans is due to an X- linked recessive gene. Both John and Cathy have normal color vision. Cathy is adopted, and knows nothing about her biological parents. After 10 years of marriage to John, Cathy has given birth to a color-blind daughter and a color-blind son. John filed for divorce, claiming that he is not the father of at least one of the children. Is John justified in his claim of nonpaternity? Yes. He cannot be the father of Cathy's son. b. Yes, He cannot be the father of either child. O c. No. He is the father of both children. d. Yes. He cannot be the father of Cathy's daughter. Next page ge ems: X Inactivation, Nondisjunction, Quiz 3 Sex-linked Traits> Jump to... Pedigree FEB 17 MacBook Air 80 DII DD F1 F2 F3 F4 F5 F6 F7 F8 F9 F10 @ #3 $4 & *
A mother is a carrier of a recessive X-linked disorder. What are the chances of her offspring being afflicted by this disorder assuming a healthy father? 100% chance for male offspring; ~0% chance for female offspring 50% chance for male offspring; ~0% chance for female offspring 0% chance for male offspring; ~0% chance for female offspring 25% chance for male offspring; ~25% chance for female offspring 50% chance for male offspring; ~50% chance for female offspring
In man, muscular dystrophy is a condition in which the muscles waste away during early life and may result in a shorter life expectancy. It is due to a sex-linked, recessive gene. A certain couple has five children – three boys (ages 1yr, 3yrs, and 10yrs old) and two girls (ages 5yrs and 7yrs old). The oldest boy shows the symptoms of this disease. You are their family physician and they come to you for advice. What would you tell them about the chances of their other children developing the disease?
Red-green color blindness is inherited as an X-linked recessive (Xc). If a color-blind man marries a woman who is heterozygous for normal vision, what would be the expected phenotypes of their children with reference to this character? In your answer, specify in your phenotype descriptions the gender of the children. (For example, don’t just say 75% of the children would be colorblind – you would instead say 100 % of the daughters would be colorblind and 50% of the sons would be colorblind. Note that this is not a correct answer; it is just to give you an idea of how to explain the correct phenotypes of the cross.)___
X‑linked, recessive diseases, such as hemophilia, are extremely rare in the population. However, many women are carriers and show no sign of the disease. The pedigree illustrates the inheritance of an X‑linked, recessive disease. Determine whether the unknown individuals are affected by the disease, unaffected by the disease, or carriers of the X‑linked recessive allele. Unaffected individuals are not carriers of the X‑linked recessive allele.
Let’s suppose that two different X-linked genes exist in mice,designated with the letters N and L. Gene N exists in a dominant,normal allele and in a recessive allele, n, that is lethal. Similarly,gene L exists in a dominant, normal allele and in a recessive allele,l, that is lethal. Heterozygous females are normal, but males thatcarry either recessive allele are born dead. Explain whether or notit would be possible to map the distance between these two genesby making crosses and analyzing the number of living and deadoffspring. You may assume that you have strains of mice in whichfemales are heterozygous for one or both genes.
X-linked ichthyosis is an X-linked recessive trait that manifests in part as dry, scaly skin (“ichthy-” = fish or fish like). Suppose a couple are considering having a child together. Parent A is heterozygous for the ichthyosis allele while Parent B is hemizygous negative for the ichthyosis allele. What is the probability their child would be unafflicted with ichthyosis but be a carrier of the ichthyosis-causing allele? a.0% b.25% c.50% d.75% e.100%
A certain type of deafness in humans is inherited as an X-linked recessive trait. A man with this type of deafness married a normal woman, and they are expecting a child. They find out that they are distantly related. Part of the family tree is shown here.How would you advise the parents about the probability of their child being a deaf boy, a deaf girl, a normal boy, or a normal girl? Be sure to state any assumptions that you make.
Color-blindness is an X-linked recessive disorder. Under what circumstances will this condition manifest in a child? Top of Form If the child is a male and its mother has the recessive allele If the child is a female and its father has the recessive allele If the child is a female and its mother has the recessive allele If the child is a male and its father has the recessive allele
In humans, red-green color-blindness is a recessive X-linked trait. A man with red-green color- blindness marries a normal-vision woman whose father was color-blind. As the genetic counselor, construct a Punnett square to determine the genotypic and phenotypic possibilities of their children. orange is due to heteroz means In human, assume that albinism is an autosomal recessive characteristic while hemophilia is X-linked recessive. An albino nonhemophiliac man has children with a normally-pigmented nonhemophiliac woman whose father was a hemophiliac and whose mother was albino. Calculate the phenotypes of the children they could produce.