Answered: Tay-Sachs disease is a recessive…

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter19: Population Genetics And Human Evolution

Section: Chapter Questions

Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...

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Tay-Sachs disease is a recessive genetic disease. Individuals with this disease rarely survive past the age of four. In the general population, approximately 1 person in 300 carries the allele for this disease. However, in some populations, including the Irish Americans, the Ashkenazi Jews and the Cajuns from Louisiana, the proportion of Tay-Sachs carriers is much higher (1 in 27 to 1 in 50) than in other populations. Which evolutionary scenario can be predicted to produce a high frequency of Tay-Sachs disease in these populations?

Select one:

a. All three populations descend from a small number of settlers

b. The Tay-Sachs allele is advantageous at the heterozygous state

c. These populations experienced disruptive selection

d. These populations experienced stabilizing selection

e. These populations have higher than average mutation rates

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