Tay-Sachs disease is a recessive genetic disease. Individuals with this disease rarely survive past the age of four. In the general population, approximately 1 person in 300 carries the allele for this disease. However, in some populations, including the Irish Americans, the Ashkenazi Jews, and the Cajuns from Louisiana, the proportion of Tay-Sachs carriers is much higher (1 in 27 to 1 in 50) than in other populations. Such high frequency of an otherwise rare allele is expected when    Question 24 options:   populations experienced disruptive selection   populations were founded by a small number of settlers   the allele is advantageous at the heterozygous state    populations have higher than average mutation rates   populations experienced stabilizing selection

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter19: Population Genetics And Human Evolution
Section: Chapter Questions
Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...
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Tay-Sachs disease is a recessive genetic disease. Individuals with this disease rarely survive past the age of four. In the general population, approximately 1 person in 300 carries the allele for this disease. However, in some populations, including the Irish Americans, the Ashkenazi Jews, and the Cajuns from Louisiana, the proportion of Tay-Sachs carriers is much higher (1 in 27 to 1 in 50) than in other populations. Such high frequency of an otherwise rare allele is expected when 

 

Question 24 options:

 

populations experienced disruptive selection

 

populations were founded by a small number of settlers

 

the allele is advantageous at the heterozygous state

 

 populations have higher than average mutation rates

 

populations experienced stabilizing selection

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