succinyl CoA?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
icon
Concept explainers
Question

One of the regulators of the TCA cycle is succinyl CoA.  Discuss the rationale for this molecule to be used to regulate the TCA cycle. 

  1. What is the metabolic role of succinyl CoA?
Expert Solution
Step 1
  • The tricarboxylic acid cycle (TCA) cycle is a series of eight catalyzed reactions as well as eight intermediates which break down the hydrocarbon substrates into carbon dioxide and water with the energy discharged to the addition of nicotinamide adenine dinucleotide that is converted from NAD+ to NADH and flavin adenine dinucleotide converted from FADH to FADH2.
  • The succinyl CoA synthetase is a major intermediate used in the tricarboxylic acid cycle which is produced from alpha-ketoglutarate by the alpha-ketoglutarate dehydrogenase via the process of decarboxylation where the coenzyme A (CoA) is added.
steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Metabolic pathways
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON