Sort the following steps of GPCR signal propagation (you may not use all the steps):A) Dephosphorylation of GPCRB) G protein dissociation to adenylate cyclase and GTP binds to the G proteinC) Ligand binding to GPCRD) G protein dissociation from GPCR and GDP binds to the G proteinE) Synthesis of CAMPF) Activation of PKAG) G protein association to adenylate cyclaseH) G protein dissociation from GPCR and GTP binds to the G proteinO F, C, H, F, BOCOB, D, A, E, HO C, H, G, E, FOA, G, H, B, E

G protein coupled receptors are protein receptors that are found closely associated with G proteins…

Answered: Sort the following steps of GPCR signal…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Compare and contrast GPCR and RTK receptors with respect to (a)structure (especially the transmembrane region), (b) activation mechanism, and (c) initial signal transduction across the membrane.
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Kinases, in general, are enzymes that Question 8 options: A) are always covalent modification, inhibitors. B) do not alter target activity. C) add phosphate groups to usually serine, tyrosine, or threonine. D) remove phosphate groups from serine, tyrosine, or threonine. E) all of the above
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Viagra works on which intra-cellular signaling pathway? a)PLC, DAG, PKC b)RTK, RAS, MAPK c)GPCR, PKB, calmodulin d)Acetylcholine, Nitric Oxide, cGMP e)GPCR, cAMP, PKA
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RTKs are receptors made of an extracellular ligand binding domain and an intracellular kinase domain (see image). Insulin binds to its RTK Insulin receptor, causing an increase in glucose absorption and storage in liver cells. EGF binds to its own RTK, EGFR and promotes cell growth through the Ras pathway. a) Explain why the same type of tyrosine kinase in two RTKs can lead to very different cellular responses. Give an example of potential cellular outputs for each of these two RTKs.
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Q40

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