Scientists have observed that individuals with LOW birthweight are MORE likely to become obese as teenagers. To study this observation in more depth, a scientist compared the methylation of the promoter region of the leptin gene in low birthweight (LBW) and normal birthweight (NBW) individuals by treating isolated DNA from these individuals with bisulfite and comparing the results to untreated DNA. The results are shown below. What conclusion can you draw?   Untreated: ATTCGATTCGCGAA Treated NBW: ATTCGATTCGCGAA Treated LBW: ATTTGATTCGTGAA   a)LBW individuals have unmethylated Cs in the promoter of the leptin gene, which ultimately leads to lower expression of the leptin gene. b)LBW individuals have methylated Cs in the promoter region of the leptin gene, which ultimately leads to lower expression of the leptin gene. c)LBW individuals have methylated Cs in the promoter region of the leptin gene, which ultimately leads to higher expression of the leptin gene. d)LBW individuals have unmethylated Cs in the promoter of the leptin gene, which ultimately leads to higher expression of the leptin gene.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Scientists have observed that individuals with LOW birthweight are MORE likely to become obese as teenagers. To study this observation in more depth, a scientist compared the methylation of the promoter region of the leptin gene in low birthweight (LBW) and normal birthweight (NBW) individuals by treating isolated DNA from these individuals with bisulfite and comparing the results to untreated DNA. The results are shown below. What conclusion can you draw?

 

Untreated:

ATTCGATTCGCGAA

Treated NBW:

ATTCGATTCGCGAA

Treated LBW:

ATTTGATTCGTGAA

Scientists have observed that individuals with LOW birthweight are MORE likely to become obese as teenagers. To study this observation in more depth, a scientist compared the methylation of the promoter region of the leptin gene in low birthweight (LBW) and normal birthweight (NBW) individuals by treating isolated DNA from these individuals with bisulfite and comparing the results to untreated DNA. The results are shown below. What conclusion can you draw?

 

Untreated:

ATTCGATTCGCGAA

Treated NBW:

ATTCGATTCGCGAA

Treated LBW:

ATTTGATTCGTGAA
 
a)LBW individuals have unmethylated Cs in the promoter of the leptin gene, which ultimately leads to lower expression of the leptin gene.
b)LBW individuals have methylated Cs in the promoter region of the leptin gene, which ultimately leads to lower expression of the leptin gene.
c)LBW individuals have methylated Cs in the promoter region of the leptin gene, which ultimately leads to higher expression of the leptin gene.
d)LBW individuals have unmethylated Cs in the promoter of the leptin gene, which ultimately leads to higher expression of the leptin gene.
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