Ruby (2008) refers to Polycystic Ovarian Syndrome (PCOS) as being an endocrine-metabolic disorder. What is meant by this, and what clinical evidence supports this characterization?

. Identify the endocrine organ described by each of the following statements. 1. located in the anterior neck; produces key hormones for metabolism 2. produces the hormones that are stored in the posterior pituitary 3. a mixed gland, located behind the stomach and close to the small intestine 4. paired glands suspended in the scrotum 5. bilobed gland located in the sella turcica 6. found in the pelvic cavity of the female, concerned with ova and female hormone production 7. found in the upper thorax overlying the heart; large during youth 8. found in the roof of the third ventricle of the brain 405

Write a summary on Structure Activity Relationship (SAR) of Estrogen? Or write a short note on SAR of Estrogen? Please write at your own words. Answer should be specific (8-10)lines

If left untreated, gonorrhea in women can lead to pelvic inflammatory disease (PID). What is PID and what are the potential consequences of contracting PID?

4. A) Define Cushing’s syndrome in terms of adrenal hormones. B) Differentiate between ACTH- and non-ACTH-dependent  Cushing’s syndrome. C) Explain two reasons why a person with Cushing’s syndrome may develop Type II diabetes mellitus. D) A person with NO existing endocrine pathologies appears to be Cushingiod but actually is in an Addisonian condition. What could have happened to cause this?

The symptoms of Cushing’s disease include abdominal obesity, hypertension, glucose intolerance (steroid diabetes), hirsutism, osteoporosis, polyuria, and polydipsia. Describe the consequences of cortisol excess that would produce each of these symptoms. Which tests can be performed to determine if a patient has primary or secondary Cushing’s disease? What would the results of these tests be for each type of disease?

Name 2 FDA approved drugs for the treatment of diabetic neuropathy and for each state its mechanism of action. Cite your source of information.

Stephanie, a woman whose family history contains severe osteoporosis, asked her doctor to prescribe estrogen after she reached menopause to reduce her risk of osteoporosis. In her family, she noted that her grandfather died of prostate cancer and her mother's sister died of breast cancer. The doctor refused to provide long-term estrogen replacement therapy. a) What are some reasons why the doctor refused to provide estrogen therapy? b) Does anything in her family history play a role in the doctor's decision? If so, what is it? c) Can the doctor provide alternative measures to prevent osteoporosis? What might those other measures be?

A female patient presents to a clinician feeling tired, hot, and sweaty. losing weight and having mood swings. After discussion, the clinician suspects Graves' disease. Explain how knowledge of feedback loops in the relevant endocrine pathway might help to diagnose Graves' disease, including the possible underlying causes and how the patient might be treated if Graves' disease is confirmed?   a detailed essay answer on this please

3. A) What results from hypersecretion of growth hormone before puberty? B) After puberty? C) Explain, in terms of hormonal effects, the reasons behind the two specific signs associated with hypersecretion of growth hormone after puberty.