RNA synthesis in eukaryotes and prokaryotes O occurs in the 3' to 5 direction. O none of the choices are correct. O is catalyzed by a DNA polymerase. O precedes DNA synthesis.

5'-GCGGTACGTTACGGCTTTACTGACCTGCAGGC-3' A. Convert this to a double strand DNA molecule by writing the complementary sequence. Be sure to correctly label the ends of the double stranded molecule B. Pick one of the two strands and write the sequence of an RNA molecule that could be transcribed from it. Again, you must correctly label the ends of the molecule.

Which of the following statements about cellular DNA metabolism is(are) TRUE? A All DNA polymerases have highi fidelity due to their 3:to-5' exonuclease activity aUracil bases appoar in DNA as a result of deamination of cytidine bases OC DNA primase synthesizes a short RNA primer that later appears at the 5 end of each Okazaki tragment. Do. DNA polymerase adds nucieotides to the 3end of a growing DNA strand DESpecial methyltransferase modifies adenines in GATC sequences of the newly synthesized DNA strands for subsequent re- OR Endonucleases are able to degrade both circular ald linear DNA molecules

DNA is damaged when a base from the DNA chain is removed after an alkylation has occurred. In a depurination reaction, the purine nitrogenous base is displaced from its sugar as shown in this reaction. Draw the mechanism for this reaction and suggest a reason why it occurs so easily. HN' P H2N .N H,O HN° + Pi ОН N- H2N° ОН ОН ОН ОН

DNA: 5’-CTCTACTATAAACTCAATAGGTCC-3’ Draw a box around the sequence where RNA polymerase will bind to the DNA. What is this sequence called? Will transcription start at this sequence, to the left of this sequence (“upstream”) or, to the right of this sequence (“downstream”)? Draw a small arrow above the DNA strand where transcription will begin. Which DNA strand will RNA polymerase transcribe? Highlight this strand with your highlighter. (Hint: RNA pol is similar to DNA pol because it can only make new RNA in the 5’ to 3’ direction. Draw in an arrow to show the direction that RNA polymerase will move along the DNA strand.

Given the following diagram of how protein AWESOME1 binds to it's target DNA, describe the potential effects of each of the 5 mutations shown below. The wild-type sequence of a helix #1 is also shown in the blue box, and all the mutations are in helix #1 (see numbers for identifying particular residues). a helix #1 R(1)-V-I-L-Y-F-W-I-M-Y-F-S-H-Y-W-R(16) #1 Predict the consequence of the following mutations: 1) Arg(1) to Glu 2) Arg(1) to Ala 3) Phe(6) to lle 4) Trp(7) to Phe 5) Met(9) to Pro in

PLEASE I ASKED 3 TIMES ON BARTELBY AND LITERALLY EVERONE GAVE A DIFFERNT ANSWER, I PROVIDED PROOF THAT THIS HAPPENED SO YOU DONT THINK IM LYING SO PLEASE READ THE QUESTION AND ANSWER CAREFULLY

1) It asks to categorize and match the "possible answers" as components of translation, transcription, DNA replicaiton or common for all:

What enzymatic activity is used to remove RNA primers at the end of DNA replication? Be specific and name the direction! need the enzymatic activity not the enzyme in question