Ribosome ER signal sequance As a polypaptde is belng made, SP binds to an ER signal sequence and causes tandationto pauisa SRP SP binds to an SRP receptor in the ER membrane, which is located next to a channel For his binding to ocour, proteins within SRP and the SRP receptor must also be bound by CTP. Cytosol ER membrane ER lumon Channel SRP receptor The GTRbinding proteins within SRP and the SRP recoptor hydrolyze their CTP, Cusing he releaie of SRP. This alows translation toresume, and the polypeptde is threaded trough a channa into the ER umen COPP

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter15: From Dna To Protein
Section: Chapter Questions
Problem 6TYK
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Referring to Figure 18.5, predict what would happen if the SRP
RNA was unable to stimulate the GTPase activities of the GTPbinding
proteins within SRP and the SRP receptor.

Ribosome
ER signal
sequance
As a polypaptde is belng made,
SP binds to an ER signal sequence
and causes tandationto pauisa
SRP
SP binds to an SRP receptor in the
ER membrane, which is located next
to a channel For his binding to ocour,
proteins within SRP and the SRP
receptor must also be bound by CTP.
Cytosol
ER membrane
ER lumon
Channel SRP receptor
The GTRbinding proteins within SRP
and the SRP recoptor hydrolyze their
CTP, Cusing he releaie of SRP. This
alows translation toresume, and the
polypeptde is threaded trough a
channa into the ER umen
COPP
Transcribed Image Text:Ribosome ER signal sequance As a polypaptde is belng made, SP binds to an ER signal sequence and causes tandationto pauisa SRP SP binds to an SRP receptor in the ER membrane, which is located next to a channel For his binding to ocour, proteins within SRP and the SRP receptor must also be bound by CTP. Cytosol ER membrane ER lumon Channel SRP receptor The GTRbinding proteins within SRP and the SRP recoptor hydrolyze their CTP, Cusing he releaie of SRP. This alows translation toresume, and the polypeptde is threaded trough a channa into the ER umen COPP
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