Proteins travel from the ER to the Golgi in COP-II coated vesicles. How is cargo incorporated into these vesicles?O A. Cargo is transported through a translocon to the vesicleB. Cargo is bound by a receptor that directly associates with COP II through an adaptor proteinO C. All cargo has the KDEL signal sequence that is recognized by the KDEL receptorD. Cargo is bound by the mannose 6 phosphate receptor that associates with COP II through an adaptor protein

The cargo or proteins are produced in the rough endoplasmic reticulum (rER) and these cargo are…

Answered: Proteins travel from the ER to the…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Similar questions

The LDL receptor is internalized via endocytosis every ten minutes and recycled to the membrane. How does the cell recycle the receptor and not the ligand (in this case LDL)? A. The high pH (~10) of the early endosome causes dissociation of LDL from the receptor and the receptor is segregated into recycling endosomes. B. The low pH (~5) of the early endosome causes dissociation of LDL from the receptor and the receptor is segregated into recycling endosomes. O C. A targeting sequence on the ligand sorts it to the late endosome/lysosome. D. This is an error-prone process, the ligand often gets recycled accidentally.
AAA is a protein found in both the cytosol as well as the nucleus. In its active state, it helps to facilitate the movement of proteins into and out of the nucleus. Specifically, AAA-alpha and AAA-beta binds to receptors on the nucleus and allows for materials to enter or exit through the channels associated with the receptors. They also play a role in dropping off cargo that import and export receptors hold onto. AAA functions are controlled by two other proteins: BBB and CCC. BBB binds onto AAA, while CCC removes BBB from AAA when they are bound. As a result, there is a BBB and CCC concentration gradient that forms between the cytosol and nucleus. During prophase I, is there a concentration gradient for BBB and CCC between the cytosol and the nucleus? Why? Is this also the case during the other phases of meiosis or the cell cycle?
G
The G-protein Ras is involved in proliferative signaling, and is mutated is a large fraction of human cancers. Almost all mutations in Ras mutate the glycine at codon 12. These mutations lock Ras in an active conformation. How will the GTPase activity of a Ras protein with a G12 mutation compare to a normal Ras protein without the mutation? (10 words maximum)
N-term N- ER Signal Sequence Part of BHCC Protein N-terminus Middle of Protein C-terminus 19a. Which parts of the BHCC protein would be: Body Text 2* 2 BHCC PROTEIN SEQUENCE # ER Stop Transfer 3 A) inside the Rough ER organelle (in the ER lumen) B) inside the Rough ER membrane (transmembrane) C) in the cytosol $ Where it is located after translation (A, B, or C) ANSWER ANSWER ANSWER 4 Middle A B % 5 ER Start Transfer I MacBook Pro 6 "1"' & 7 FLEEEEE C-term C
With reference to named examples, give a detailed account of the molecules and processes involved in trafficking soluble and membrane proteins from the Trans Golgi Network (TGN) to lysosomes. Include in your answer an explanation of how the trafficking machinery is recycled back, to the Trans Golgi Network in each case.
Explain Why when cellular signals shift in balance toward pro-apoptotic proteins, the cell is more likely to undergo apoptosis.
Match the protein on the left with the type of activation of that protein on the right STAT Smad PKA Ras NFKB Nuclear receptor [Choose] [Choose] GTP binding serine phosphorylation Interaction with Galpha Cleavage by y-secretase destruction of a protein by proteasome tyrosine phosphorylation second messenger ligand binding [Choose] [Choose] [Choose]
What is an "orphaned response regulator?" O A response regulator that is nonfunctional because it has no partner histidine kinase O A response regulator whose partner histidine kinase is unknown O A fusion of a response regulator and a histidine kinase to create a single functional protein O A response regulator whose partner histidine kinase is not placed side by side with it in the genome
The fragments of huntingtin protein also form aggregates with a nuclear transport protein known as Ran-GAP. How does Ran-GAP aggregating with huntingtin protein fragments disrupt nuclear protein transport?
Describe the structure of SRP in eukaryotes, and outline its role intargeting proteins to the ER membrane.

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