House mouse (Mus musculus) Gene of interest: B4galnt2 (encodes glycosyltransferase enzyme) Allele R: Associated with prolonged bleeding due to issues with blood clotting; associated with resistance to bacterial infections due to absence of intestinal expression. Allele C: Associated with increased susceptibility to bacterial infections; not associated with prolonged bleeding. A B C The population is closed; there are no new mice coming in. The cages are setup to allow for random mating. The B4galnt2 gene is not associated with any mating preferences or non-random mating patterns. Studies have shown that mutations in this locus are extremely rare. The population is EXTREMELY large. The population is kept in well maintained environment, free of bacterial infections. The mouse food is supplemented with a low dose of blood coagulator, which helps the blood clot and eliminates any prolonged bleeding. None of the genotypes display any side effects to this medication. The population is closed; there are no new mice coming in. The cages are setup to allow for random mating. The B4galnt2 gene is not associated with any mating preferences or non-random mating patterns. Studies have shown that mutations in this locus are extremely rare. The population is EXTREMELY large. The mouse food is supplemented with a low dose of blood coagulator, which helps the blood clot and eliminates any prolonged bleeding. None of the genotypes display any side effects to this medication. The population is closed; there are no new mice coming in. The cages are setup to allow for random mating. The B4galnt2 gene is not associated with any mating preferences or non-random mating patterns. Studies have shown that mutations in this locus are extremely rare. The population is kept in well maintained environment, free of bacterial infections. The mouse food is supplemented with a low dose of blood coagulator, which helps the blood clot and eliminates any prolonged bleeding. None of the genotypes display any side effects to this medication.

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After challenges containing the outbreak, the Kelatavicla lab had to close in January 2018 . Six mice are given antibiotics, certified bad bacteria free, and are shipped to a lab in Montreal. Among the 6 mice, which have been carefully chosen, the frequency of the R allele is 0.5 . The Montreal lab maintains this population under the conditions described in column C for several years. Predict what might happen to the frequency of the R allele over the next several years. Justify your choice with concepts  and how they apply to the given case. Ensure you use appropriate terminology to name/identify the concepts and processes.

House mouse (Mus musculus)
Gene of interest: B4galnt2 (encodes glycosyltransferase enzyme)
Allele R: Associated with prolonged bleeding due to issues with blood clotting; associated with resistance to bacterial infections due
to absence of intestinal expression.
Allele C: Associated with increased susceptibility to bacterial infections; not associated with prolonged bleeding.
A
B
C
The population is closed; there are no new mice coming in.
The cages are setup to allow for random mating. The
B4galnt2 gene is not associated with any mating preferences
or non-random mating patterns.
Studies have shown that mutations in this locus are
extremely rare.
The population is EXTREMELY large.
The population is kept in well maintained environment, free
of bacterial infections.
The mouse food is supplemented with a low dose of blood
coagulator, which helps the blood clot and eliminates any
prolonged bleeding. None of the genotypes display any side
effects to this medication.
The population is closed; there are no new mice
coming in.
The cages are setup to allow for random mating.
The B4galnt2 gene is not associated with any
mating preferences or non-random mating
patterns.
Studies have shown that mutations in this locus are
extremely rare.
The population is EXTREMELY large.
The mouse food is supplemented with a low dose
of blood coagulator, which helps the blood clot
and eliminates any prolonged bleeding. None of
the genotypes display any side effects to this
medication.
The population is closed; there are no new mice
coming in.
The cages are setup to allow for random mating.
The B4galnt2 gene is not associated with any
mating preferences or non-random mating
patterns.
Studies have shown that mutations in this locus are
extremely rare.
The population is kept in well maintained
environment, free of bacterial infections.
The mouse food is supplemented with a low dose
of blood coagulator, which helps the blood clot
and eliminates any prolonged bleeding. None of
the genotypes display any side effects to this
medication.
Transcribed Image Text:House mouse (Mus musculus) Gene of interest: B4galnt2 (encodes glycosyltransferase enzyme) Allele R: Associated with prolonged bleeding due to issues with blood clotting; associated with resistance to bacterial infections due to absence of intestinal expression. Allele C: Associated with increased susceptibility to bacterial infections; not associated with prolonged bleeding. A B C The population is closed; there are no new mice coming in. The cages are setup to allow for random mating. The B4galnt2 gene is not associated with any mating preferences or non-random mating patterns. Studies have shown that mutations in this locus are extremely rare. The population is EXTREMELY large. The population is kept in well maintained environment, free of bacterial infections. The mouse food is supplemented with a low dose of blood coagulator, which helps the blood clot and eliminates any prolonged bleeding. None of the genotypes display any side effects to this medication. The population is closed; there are no new mice coming in. The cages are setup to allow for random mating. The B4galnt2 gene is not associated with any mating preferences or non-random mating patterns. Studies have shown that mutations in this locus are extremely rare. The population is EXTREMELY large. The mouse food is supplemented with a low dose of blood coagulator, which helps the blood clot and eliminates any prolonged bleeding. None of the genotypes display any side effects to this medication. The population is closed; there are no new mice coming in. The cages are setup to allow for random mating. The B4galnt2 gene is not associated with any mating preferences or non-random mating patterns. Studies have shown that mutations in this locus are extremely rare. The population is kept in well maintained environment, free of bacterial infections. The mouse food is supplemented with a low dose of blood coagulator, which helps the blood clot and eliminates any prolonged bleeding. None of the genotypes display any side effects to this medication.
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