Question 1. Cytoplasmic kinases are typically activated in the cytoplasm: A. as part of a cascade. B. and then immediately inactivated to halt the signaling pathway. C. downstream of an activated receptor. D. A and B E. A and C

QUESTION 3 Differential stains function to O A. kill certain cells while allowing others to remain alive. O B. stain all cell types the same. O C. differentiate between bacteria and archaea. O D. highlight/distinguish differences between cell types and/or parts of a cell. O . Two of A - D are correct.

Question one parts A though e a. You have a plan to make the cellular signaling peptide RGD (Arg-Gly-Asp). If you are beginning from the Arginine (Arg) amino acid, which amino acid(s) will require NH2 protection to optimize the synthesis? A) All 3 amino acids will need NH2 protection B) Gly and Asp will need NH2 protection C) Arg and Gly will need NH2 protection D) Only Arg b. Which of the following amino acids will not produce a purple color (indicative of 2 ninhydrin molecules binding) when reacted with ninhydrin? A) phenylalanine B) valine C) proline D) histidine c. If you had a mixture of leucine, arginine, and glutamic acid in a pH of 6 and applied a drop onto paper connected to an electrophoresis apparatus. Which of these would move toward the cathode (-). A) Leucine B) Arginine C) Glutamic Acid D) None of them d. True/False - Dicyclehexvlcarbodiimide is a typical reagent in peptide synthesis for protecting carboxylic acid groups. e. True/False t-butoxycarbonyl dicarbonate…

QUESTION 19 Which enzyme (Enzyme 1, circle; Enzyme 2 square) has the worst affinity for the substrate? 5.0 4.0 EnzGraph 3.0 8 2.0 1.0 0.0 10 15 20 25 30 35 40 45 50 substrate (mM) Enz1 Enz2 A. Enzyme 1 (circles) B. Enzyme 2 (squares) C. cannot tell with information given D. both have the same affinity

Question 5. What is typically the purpose of using a transmission electron microscope to image a sample? A. To obtain greater magnification. B. To obtain greater resolution. C. To obtain greater resolution and magnification. D. To observe organelles. E. None of these answers is correct.

Question 12 Match the tenzyme with the post translational moidification v pyruvate detydrogenase complex a. lipoylysine v aconitase b. phosphotylation an serine v phosphoglycerate mutase c ron-sultur center v phosphoglucomutese d. phosphorylation an histidine A Moving to another question will save this response.

QUESTION 19 Receptor-mediated signaling might affect which of the following cellular processes? OA. Cell growth OB. Cell cycle OC. Transcription OD. Apoptosis O E. All of the above QUESTION 20 Which of the following does NOT function as a second messenger in cell signaling pathways? OA cholesterol OB. CAMP O C. IP3 O D. Calcium ions (Ca2+) QUESTION 21 In the insulin-signaling cascade, PTEN removes a phosphate group from the membrane lipid PIP3 to form PIP2. What type of enzyme is PTEN? OA. Polymerase OB. Phosphatase OC. Kinase OD. Lipase O E. Ligase

QUESTION 49 Which of the following is not true/accurate with respect to p53?   a. is a tumor-suppressor   b. is a transcription factor that promotes transcription of inhibitors of the cell cycle   c. is an oncogene   d. is named for its molecular mass (in kiloDaltons)

QUESTION 9 Which of these is a risk factor for developing cancer?   A. growing older   B. genetic inheritance   C. exposure to carcinogens (toxins that can damage DNA)   D. all of the above are true   IT IS NOT D

Question 4. Which of the following statements are true of kinases? A. They always bind to a dimeric ligand. B. They phosphorylate themselves or another protein. C. They must be associated with a G-protein to function. D. They always contain seven membrane-spanning domains. E. They always dephos phorylate proteins.