Please discuss how digitoxin provides a positive inotropic effect and is used to treat congestive heart failure.

what cells are affected by drugs that have chronotropic effects ?

Describe the mechanism of action of intravenous injection of epinephrine or norepinephrine. What effect is expected on heart rate and blood pressure? How it affects blood vessels and circulation?

Discuss the SARs of 4 selective Beta Blockers and 1 combined beta blockers.

What are the specific pharmacogenetic factors that influence the effectiveness and toxicity of anticoagulant drugs in patients with inherited thrombophilia?

A patient with severe hypotension has dopamine ordered at 5 mcg/kg/min. The patient weighs 67 kg. The concentration of dopamine is 3 g in 500 mL of normal saline. How many mL per hour should the IV pump be programmed for? Round to the nearest tenth and list only the number.

Antihypertensive treatment with calcium channel blockers (CCBs) is often offered to patients with stage 2 hypertension. Please describe the intracellular signaling events, mechanisms of action on blood vessels and important adverse effects of CCBs. In addition, describe considerations such as the age of a patient when prescribing a CCB at the first stage of antihypertensive therapy according to NICE guidelines.

a patient has been prescribed an alteplase infusion.   describe the mechanism of action, and aim of therapy for Amelia, identify guidelines for this medication, and  identify ONE risk of this therapy

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What is the function of an anticoagulant?